O6503
L -鸟氨酸 单盐酸盐
BioReagent, suitable for cell culture, ≥99%
别名:
(S)-2,5-二氨基戊酸 单盐酸盐
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关于此项目
经验公式（希尔记法）:
C5H12N2O2 · HCl
化学文摘社编号:
分子量:
168.62
UNSPSC Code:
12352209
NACRES:
NA.75
PubChem Substance ID:
EC Number:
221-678-6
Beilstein/REAXYS Number:
3625847
MDL number:
产品名称
L -鸟氨酸 单盐酸盐, BioReagent, suitable for cell culture, ≥99%
InChI key
GGTYBZJRPHEQDG-WCCKRBBISA-N
InChI
1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
SMILES string
Cl.NCCC[C@H](N)C(O)=O
biological source
microbial
product line
BioReagent
assay
≥99%
form
powder
packaging
pkg of 100 g
pkg of 25 g
technique(s)
cell culture | mammalian: suitable
impurities
ammonia and citrulline, essentially free
solubility
H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow
Quality Level
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Application
L-鸟氨酸一盐酸已被用于：
- 作为用于细胞生长测定的Dulbecco′s modified eagle medium（DMEM）培养基的一种补剂
- 作为用于原代人肝细胞（PHH）培养的标准培养基的一种成分
- 作为肌酸合成抑制剂
Biochem/physiol Actions
L-鸟氨酸可作为多胺的前体。它在新生雏鸡大脑中可作为急性饱腹信号以调节食物的摄入。
L-鸟氨酸可用作培养基补剂以支持多胺的生物合成。
General description
L-鸟氨酸是L-精氨酸的功能代谢产物。
L-鸟氨酸是一种非遗传密码编码的氨基酸。它是在精氨酸酶分解精氨酸的过程中形成的，并参与尿素循环。鸟氨酸是形成包括精胺、亚精胺和腐胺在内的多胺家族的起点。
Other Notes
精氨酸通过精氨酸酶降解所得产物
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Arginine
Profiles of Drug Substances, Excipients, and Related Methodology, 27, 1-32 (2001)
L-Ornithine is a potential acute satiety signal in the brain of neonatal chicks
Tran PV, et al.
Physiology & Behavior, 155, 141-148 (2016)
Z N Canellakis et al.
The Yale journal of biology and medicine, 62(5), 481-491 (1989-09-01)
The polyamines and their derivatives are essential for life in eukaryotic and most prokaryotic cells, but their exact role in preserving cell function is not clear. These polyamines provide endogenous cations and thus participate in regulation of the intracellular pH;
Arginase 2 suppresses renal carcinoma progression via biosynthetic cofactor pyridoxal phosphate depletion and increased polyamine toxicity
Ochocki JD, et al.
Cell Metabolism, 27(6), 1263-1280 (2018)
Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
Ji L, et al.
Immunity, 51(2), 272-284 (2019)
商品
Discover L-ornithine, an important amino acid supplement, explore how L-ornithine is used in CHO and iPSC culture, and discover how poly-L-ornithine is used to enhance cell attachment.
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