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Merck
CN

O5502

Sigma-Aldrich

S-Octylglutathione

suitable for ligand binding assays

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About This Item

经验公式(希尔记法):
C18H33N3O6S
CAS号:
分子量:
419.54
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:

产品名称

S-Octylglutathione,

表单

solid

技术

ligand binding assay: suitable

储存温度

2-8°C

SMILES字符串

CCCCCCCCSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O

InChI

1S/C18H33N3O6S/c1-2-3-4-5-6-7-10-28-12-14(17(25)20-11-16(23)24)21-15(22)9-8-13(19)18(26)27/h13-14H,2-12,19H2,1H3,(H,20,25)(H,21,22)(H,23,24)(H,26,27)

InChI key

MJWCZWAVSJZQNL-UHFFFAOYSA-N

生化/生理作用

S-octylglutathione is a competitive inhibitor for glutathione S-transferases.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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G Davidson et al.
Biochemistry, 40(15), 4569-4582 (2001-04-11)
Escherichia coli glyoxalase I (GlxI) is a metalloisomerase that is maximally activated by Ni(2+), unlike other known GlxI enzymes which are active with Zn(2+). The metal is coordinated by two aqua ligands, two histidines (5 and 74), and two glutamates
M Kurata et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 103(4), 863-867 (1992-12-01)
1. Phenol compounds (ellagic acid, quercetin and purpurogallin), glutathione analogues (S-hexylglutathione and S-octylglutathione) and a diuretic drug (ethacrynic acid) were compared for their inhibitory effects on glutathione S-transferase (GST), glutathione reductase (GR) and glutathione peroxidase (GSH-Px) in the canine erythrocytes.
I Eberhardt et al.
Prostaglandins, 41(2), 185-199 (1991-02-01)
Pituitary cells produce leukotrienes (LTs) and respond to exogenous administration of LTs by releasing gonadotropins. Specific high affinity leukotriene C4 (LTC4) binding has been found in membrane preparations of bovine anterior pituitaries. Unlabelled LTC4 displaced specific [3H]LTC4 binding. Other leukotrienes
E Ortiz-Salmerón et al.
Biochimica et biophysica acta, 1548(1), 106-113 (2001-07-14)
The binding of three competitive glutathione analogue inhibitors (S-alkylglutathione derivatives) to glutathione S-transferase from Schistosoma japonicum, SjGST, has been investigated by isothermal titration microcalorimetry at pH 6.5 over a temperature range of 15--30 degrees C. Calorimetric measurements in various buffer
M A Tirmenstein et al.
Biochimica et biophysica acta, 995(2), 174-180 (1989-04-06)
Glutathione protects isolated rat liver nuclei against lipid peroxidation by inducing a lag period prior to the onset of peroxidation. This GSH-dependent protection was abolished by exposing isolated nuclei to the glutathione S-transferase inhibitor S-octylglutathione. In incubations containing 0.2 mM

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