所有图片(1)
About This Item
线性分子式:
OsO4
CAS号:
分子量:
254.23
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
表单:
powder
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蒸汽密度
8.8 (vs air)
质量水平
蒸汽压
7 mmHg ( 20 °C)
表单
powder
反应适用性
reagent type: oxidant
沸点
130 °C (lit.)
mp
39.5-41 °C (lit.)
SMILES字符串
O=[Os](=O)(=O)=O
InChI
1S/4O.Os
InChI key
VUVGYHUDAICLFK-UHFFFAOYSA-N
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一般描述
四氧化锇(OsO4)是四面体构型的对称分子，含有第三过渡系过渡金属锇。四氧化锇可作为电镜的染料和非凝固型固定剂，主要用于组织病理学实验室中的生物组织检测。标本用四氧化锇再固定(postfix)可确保脂质保存。
应用
四氧化锇已作为固定剂用于短杆菌Brevibacterium mcbrellneri处理，以及经姜黄素处理的人癌细胞系的扫描电镜观察。还可作为固定剂用于弓形虫Toxoplasma gondii骨骼肌的超微结构分析。
生化/生理作用
四氧化锇化学性结合脂质，使其不溶；固定后仅余7%的脂质可提取。因此，用四氧化锇固定后，由磷脂组成的细胞膜会变黑且电子密度提高。它还可在石蜡处理过程中固定切片中的少量脂肪。
其他说明
由于四氧化锇的危害性，建议在使用该化学品时使用安瓿开启器。
警示用语：
Danger
危险分类
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
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