Amino Acid Sequence
H-Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg-OH
一般描述
卵清蛋白(323-339)是由B细胞表位环绕的蛋清蛋白,被特异性IgE抗体结合。除此之外,它还含有CD4+ T细胞表位。
该肽是卵清蛋白的第II类主要MHC限制性T细胞表位,用于研究免疫性过敏反应,如哮喘、食物过敏等。
应用
卵清蛋白(323-339)(鸡,日本鹌鹑)已被用于诱导小鼠过敏性哮喘。
生化/生理作用
卵清蛋白(OVA)肽323-339在隔离的BALB/c小鼠体内介导25-35%的T细胞对完整OVA的反应。OVA 323-339被广泛用于测定第II类主要组织相容性复合体(MHC)-肽结合特征和T细胞活化特征。
在两个功能不同的辅助因子的帮助下,卵清蛋白(323-339)肽可与组织相容性复杂的II类I-A(d)蛋白结合。
外形
由0.1% TFA水溶液冷冻干燥而得
其他说明
从0.1% TFA的H2O溶液冷冻干燥而得
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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