N9410
还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐
~98%, pkg of 5 mg (per vial)
别名:
β-DPNH, β-NADH, Coenzyme I reduced 二钠盐, Diphosphopyridine nucleotide reduced 二钠盐
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关于此项目
经验公式（希尔记法）:
C21H27N7Na2O14P2
化学文摘社编号:
分子量:
709.40
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
EC Number:
210-123-3
Beilstein/REAXYS Number:
5230241
MDL number:
Form:
powder
Assay:
~98%
assay
~98%
Quality Level
form
powder
packaging
pkg of 5 mg (per vial)
SMILES string
[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
InChI
1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20-,21+;;/m0../s1
InChI key
QRGNQKGQENGQSE-QUWMEQBESA-L
Application
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
Biochem/physiol Actions
电子供体
Preparation Note
溶液应新鲜制备并及时使用。
Other Notes
根据 UV-Vis 测定的 NADH 含量包装。
这是 NADH 的常见形式；不要与 α 混淆-NADH。
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存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
Weihai Ying
Frontiers in bioscience : a journal and virtual library, 11, 3129-3148 (2006-05-25)
Increasing evidence has indicated that NAD+ and NADH play critical roles not only in energy metabolism, but also in cell death and various cellular functions including regulation of calcium homeostasis and gene expression. It has also been indicated that NAD+
Richard P Ebstein et al.
FEBS letters, 585(11), 1529-1536 (2011-05-12)
Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have
"Clocks" in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging.
Shin-Ichiro Imai
Biochimica et biophysica acta, 1804(8), 1584-1590 (2009-11-10)
SIR2 (silent information regulator 2) proteins, now called "sirtuins," are an evolutionarily conserved family of NAD-dependent protein deacetylases/ADP-ribosyltransferases. Sirtuins have recently attracted major attention in the field of aging research, and it has been demonstrated that SIR2 and its orthologs
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| N9410-15VL | 04061834118831 |
| N9410-3X1VL | 04061837151606 |
| N9410-1VL | 04061837144103 |