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Merck
CN

N9407

Neuropeptide Y Fragment 3-36 human, rat

≥95% (HPLC)

别名:

NPY 3-36

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关于此项目

经验公式(希尔记法):
C175H269N53O54S
化学文摘社编号:
分子量:
4011.40
UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
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Quality Level

assay

≥95% (HPLC)

form

powder

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... NPY(4852)

General description

Neuropeptide Y (NPY) is a regulatory protein consisting of 36 amino acids. It is ubiquitously expressed in the heart and brain. NPY is a member of pancreatic polypeptide family. The gene encoding this protein is localized on human chromosome 7p15.

Biochem/physiol Actions

Endogenous neuropeptide that selectively binds to Y<SUB>2</SUB> and Y<SUB>5</SUB> receptors.
Neuropeptide Y (NPY) plays a vital role in various processes like feeding behavior, anxiety, epilepsy, circadian rhythm, sleep, pain and drug addiction. It also modulates appetite, body weight and obesity. The protein has potent vasoactive effects on the cardiovascular system and controls central endocrine secretion. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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R Mentlein et al.
Regulatory peptides, 49(2), 133-144 (1993-12-10)
Neuropeptide Y, peptide YY and pancreatic polypeptide share an evolutionary conserved proline-rich N-terminal sequence, a structure generally known to be inert to the attack of common proteinases, but a potential target for specialized proline-specific aminopeptidases. Purified human dipeptidyl peptidase IV
Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity
C Roche
Diabetologia, 40, 671?675-671?675 (1997)
Eitezaz Mahmood et al.
European journal of pharmacology, 882, 173261-173261 (2020-06-14)
Neuropeptide-Y (NPY) leads to angiogenesis and remodeling of the ischemic myocardium. The objective of this study is to assess the therapeutic potential of NPY in a model of acute myocardial ischemia using a nanoparticles delivery system targeted to tissue with



全球贸易项目编号

货号GTIN
N9407-250UG04061834118824