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Merck
CN

N8661

Sigma-Aldrich

5′-核苷酸酶 来源于西部菱背响尾蛇 毒液

lyophilized powder, ≥200 units/mg protein

别名:

5′-核糖核苷酸磷酸水解酶

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About This Item

CAS号:
Beilstein:
1301486
MDL编号:
UNSPSC代码:
12352204

表单

lyophilized powder

比活

≥200 units/mg protein

运输

dry ice

储存温度

−20°C

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单位定义

在 pH 9.0 和 37°C 下,一单位本品每分钟可从 5′-腺嘌呤核苷酸中水解出 1.0μmol 无机磷。

外形

冻干粉,主要含均衡的海藻糖、HEPES 以及 CaCl2

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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Smita S Iyer et al.
European journal of immunology, 43(12), 3219-3232 (2013-09-14)
CD4(+) T follicular helper (TFH) cells are central for generation of long-term B-cell immunity. A defining phenotypic attribute of TFH cells is the expression of the chemokine R CXCR5, and TFH cells are typically identified by co-expression of CXCR5 together
Francis Coffey et al.
The Journal of experimental medicine, 211(2), 329-343 (2014-02-05)
Numerous studies indicate that γδ T cell receptor (γδTCR) expression alone does not reliably mark commitment of early thymic progenitors to the γδ fate. This raises the possibility that the γδTCR is unable to intrinsically specify fate and instead requires
Bertrand Allard et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(20), 5626-5635 (2013-08-29)
Monoclonal antibodies (mAb) that block programmed death (PD)-1 or cytotoxic T lymphocyte antigen (CTLA-4) receptors have been associated with durable clinical responses against a variety of cancer types and hold great potential as novel cancer therapeutics. Recent evidence suggest that
Bertrand Allard et al.
International journal of cancer, 134(6), 1466-1473 (2013-08-29)
CD73 is an ecto-nucleotidase overexpressed in various types of tumors that catabolizes the generation of extracellular adenosine, a potent immunosuppressor. We and others have shown that targeted blockade of CD73 can rescue anti-tumor T cells from the immunosuppressive effects of
Paul A Beavis et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14711-14716 (2013-08-22)
CD73 inhibits antitumor immunity through the activation of adenosine receptors expressed on multiple immune subsets. CD73 also enhances tumor metastasis, although the nature of the immune subsets and adenosine receptor subtypes involved in this process are largely unknown. In this

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