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Merck
CN

N8535

β-烟酰胺腺嘌呤二核苷酸

greener alternative

pkg of 50 mg (per vial)

别名:

β-DPN, β-NAD, DPN, 二磷酸吡啶核苷酸, 氧化型辅酶 I, 辅酶, 辅酶 1

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关于此项目

经验公式（希尔记法）:
C21H27N7O14P2
化学文摘社编号:
53-84-9
分子量:
663.43
NACRES:
NA.51
PubChem Substance ID:
57654452
eCl@ss:
39200202
UNSPSC Code:
41106305
EC Number:
200-184-4
MDL number:
MFCD00036253
Beilstein/REAXYS Number:
3584133
Form:
powder

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产品名称

β-烟酰胺腺嘌呤二核苷酸, pkg of 50 mg (per vial)

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

SMILES string

NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

form

powder

packaging

pkg of 50 mg (per vial)

Quality Level

200

Gene Information

human ... ESR1(2099), ESR2(2100)

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

DfS-Developed

storage temp.

−20°C

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相关类别

Application

β-烟酰胺腺嘌呤二核苷酸（NAD+）和还原型 β-烟酰胺腺嘌呤二核苷酸（NADH）构成一个辅酶氧化还原对（NAD +：NADH），参与广泛的酶催化氧化还原反应。除了其氧化还原功能外，NAD+/NADH 是 ADP-核糖基转移酶（ADP-核糖基转移酶；聚（ADP-核糖）聚合酶）反应中的 ADP-核糖单元的供体，也是环状 ADP-核糖（ADP-核糖基环化酶）的前体。

Biochem/physiol Actions

电子受体

Other Notes

本品是普通型 NAD。
根据由紫外可见分光光度计测定的 NAD 含量包装。

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000318878
0000318878
SLCN5906
SLCF2643
SLCB5594

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Melanie M Hoehl et al.
Journal of agricultural and food chemistry, 60(25), 6349-6358 (2012-05-29)
Real-time on-site monitoring of analytes is currently in high demand for food contamination, water, medicines, and ingestible household products that were never tested appropriately. Here we introduce chemical methods for the rapid quantification of a wide range of chemical and
Richard P Ebstein et al.
FEBS letters, 585(11), 1529-1536 (2011-05-12)
Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have
Ana P Gomes et al.
Cell, 155(7), 1624-1638 (2013-12-24)
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
Jeerus Sucharitakul et al.
The Journal of biological chemistry, 288(49), 35210-35221 (2013-10-17)
3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is an NADH-specific flavoprotein monooxygenase that catalyzes the para-hydroxylation of 3-hydroxybenzoate (3HB) to form 2,5-dihydroxybenzoate (2,5-DHB). Based on results from stopped-flow spectrophotometry, the reduced enzyme-3HB complex reacts with oxygen to form a C4a-peroxy
Michael O Hottiger
FEBS letters, 585(11), 1595-1599 (2011-03-23)
ADP-ribosylation is a covalent post-translational protein modification catalyzed by ADP-ribosyltransferases and is involved in important processes such as cell cycle regulation, DNA damage response, replication or transcription. Histones are ADP-ribosylated by ADP-ribosyltransferase diphtheria toxin-like 1 at specific amino acid residues
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