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Merck
CN

N8285

Sigma-Aldrich

β-烟酰胺腺嘌呤二核苷酸

pkg of 10 mg (per vial)

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别名:
β-DPN, β-NAD, DPN, 二磷酸吡啶核苷酸, 氧化型辅酶 I, 辅酶, 辅酶 1
经验公式(希尔记法):
C21H27N7O14P2
CAS号:
分子量:
663.43
Beilstein:
3584133
EC 号:
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
39200202
PubChem化学物质编号:
NACRES:
NA.51

形式

powder

质量水平

包装

pkg of 10 mg (per vial)

储存温度

−20°C

SMILES字符串

NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

基因信息

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应用

β-烟酰胺腺嘌呤二核苷酸(β-NAD)用于制备脱乙酰基微管蛋白。也用于口腔成纤维细胞裂解物 UDP-葡萄糖-6-氢化酶(UGDH)的酶活性测定。

生化/生理作用

β-烟酰胺腺嘌呤二核苷酸(β-NAD)是神经调节剂和抑制性神经递质,是嘌呤能(P2Y1)受体的激动剂。
β-烟酰胺腺嘌呤二核苷酸(NAD+)和 β-还原型烟酰胺腺嘌呤二核苷酸(NADH)包含辅酶氧化还原对(NAD + NADH),参与一系列酶催化氧化还原反应。 除了其氧化还原功能外,NAD +/NADH 是 ADP-核糖基转移酶(ADP-核糖基转移酶;聚(ADP-核糖)聚合酶)反应中的 ADP-核糖单元的供体,也是环状ADP-核糖(ADP-核糖基环化酶)的前体。
电子受体

其他说明

本品是普通型 NAD。
根据由紫外可见分光光度计测定的 NAD 含量包装。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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