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Merck
CN

N8271

Sigma-Aldrich

α(2→3,6,8,9) 神经氨酸酶 来源于产脲节杆菌

recombinant, expressed in E. coli, buffered aqueous solution

别名:

神经氨酸酶 来源于产脲节杆菌, 唾液酸酶, 神经氨酸苷酶

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.32

重组

expressed in E. coli

质量水平

表单

buffered aqueous solution

比活

≥135 units/mg protein

分子量

88 kDa
95 kDa

异质活性

β-Galactosidase, α-mannosidase, β-hexosaminidase, α-fucosidase, and proteases, none detected

运输

wet ice

储存温度

2-8°C

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生化/生理作用

从复合寡糖中释放α(2→3)、α(2→6)、α(2→8)和 α(2→9)-连接的N-乙酰神经氨酸。

包装

本品为5倍浓缩的反应缓冲液(250 mM磷酸钠,pH 6.0)。

单位定义

一个酶活性单位是指在pH 5.0、37℃下,每分钟水解1 μmole的4-甲基伞形酮α-D-N-乙酰神经氨酸苷所需的酶量。

外形

溶于20mM Tris-HCl (pH 7.5)和20 mM NaCl的溶液中。

制备说明

表达于无糖苷酶的宿主中。

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nenad Macesic et al.
The Medical journal of Australia, 198(7), 370-372 (2013-04-16)
To review cases of nosocomial influenza and compare the epidemiology, clinical characteristics and outcomes with community-acquired cases. Prospective case series of adults hospitalised with influenza during April - November of 2010 and 2011 using a hospital-based sentinel surveillance system. A
Michael Worobey et al.
Nature, 508(7495), 254-257 (2014-02-18)
Zoonotic infectious diseases such as influenza continue to pose a grave threat to human health. However, the factors that mediate the emergence of RNA viruses such as influenza A virus (IAV) are still incompletely understood. Phylogenetic inference is crucial to reconstructing
Audu J Natala et al.
Journal of medical entomology, 50(1), 85-93 (2013-02-23)
Amblyomma variegatum F. are obligate hematophagous ectoparasites of livestock that serve as the vectors of Ehrlichia ruminantium (formerly known as Cowdria ruminantium), the causative agent of heartwater disease. In the light of the fact that they are blood-feeding, their salivary
Dominic Meusch et al.
Nature, 508(7494), 61-65 (2014-02-28)
Tripartite Tc toxin complexes of bacterial pathogens perforate the host membrane and translocate toxic enzymes into the host cell, including in humans. The underlying mechanism is complex but poorly understood. Here we report the first, to our knowledge, high-resolution structures
Johan Nordholm et al.
The Journal of biological chemistry, 288(15), 10652-10660 (2013-03-01)
Interactions that facilitate transmembrane domain (TMD) dimerization have been identified mainly using synthetic TMDs. Here, we investigated how inherent properties within natural TMDs modulate their interaction strength by exploiting the sequence variation in the nine neuraminidase subtypes (N1-N9) and the

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