N8130
4-硝基苯基乙酸酯
esterase substrate, chromogenic, ≥98% (TLC), powder or crystals
别名:
乙酸4-硝基苯酯
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关于此项目
线性分子式:
CH3CO2C6H4NO2
化学文摘社编号:
分子量:
181.15
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
212-593-5
MDL number:
Beilstein/REAXYS Number:
515874
产品名称
4-硝基苯基乙酸酯, esterase substrate
InChI key
QAUUDNIGJSLPSX-UHFFFAOYSA-N
InChI
1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
SMILES string
CC(=O)Oc1ccc(cc1)[N+]([O-])=O
assay
≥98% (TLC)
form
powder or crystals
mp
75-77 °C (lit.)
storage temp.
−20°C
Quality Level
Gene Information
human ... PON1(5444)
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Application
4-硝基苯基乙酸酯已用于：
- 评估人胚肾细胞系中的酯酶活性
- 碳酸酐酶抑制试验
- 通过牛血清白蛋白的酯酶活性，将其转换为 对硝基苯酚（p-NP）的研究中
- 作为确定小鼠肝细胞中羧酸酯酶（CES）活性的底物
- 研究磁性CLEAs基质中交联酶聚集体（CLEAs）和磁性氧化铁纳米粒子（MIONPs）的生物共轭优势
General description
生色酯酶底物。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
存储类别
5.1B - Oxidizing hazardous materials
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves, type N95 (US)
Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
Emmanuel Vázquez-Mayorga et al.
International journal of molecular sciences, 17(8) (2016-08-25)
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both
Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae
Afzal K, et al.
Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)
Michelle R Baker et al.
Biochemistry research international, 2011, 739712-739712 (2011-09-16)
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and
Impact of diet on irinotecan toxicity in mice
Mallick P, et al.
Chemico-Biological Interactions, 291, 87-94 (2018)
Beyond esterase-like activity of serum albumin. Histidine-(nitro) phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light
Kowacz M and Warszynski P
arXiv (2018)
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