推荐产品
产品名称
4-硝基苯基乙酸酯, esterase substrate
质量水平
方案
≥98% (TLC)
表单
powder or crystals
mp
75-77 °C (lit.)
储存温度
−20°C
SMILES字符串
CC(=O)Oc1ccc(cc1)[N+]([O-])=O
InChI
1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
InChI key
QAUUDNIGJSLPSX-UHFFFAOYSA-N
基因信息
human ... PON1(5444)
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应用
4-硝基苯基乙酸酯已用于：
- 评估人胚肾细胞系中的酯酶活性
- 碳酸酐酶抑制试验
- 通过牛血清白蛋白的酯酶活性，将其转换为 对硝基苯酚（p-NP）的研究中
- 作为确定小鼠肝细胞中羧酸酯酶（CES）活性的底物
- 研究磁性CLEAs基质中交联酶聚集体（CLEAs）和磁性氧化铁纳米粒子（MIONPs）的生物共轭优势
底物
生色酯酶底物。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
储存分类代码
5.1B - Oxidizing hazardous materials
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
个人防护装备
Eyeshields, Gloves, type N95 (US)
Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
Emmanuel Vázquez-Mayorga et al.
International journal of molecular sciences, 17(8) (2016-08-25)
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both
Michelle R Baker et al.
Biochemistry research international, 2011, 739712-739712 (2011-09-16)
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and
Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae
Afzal K, et al.
Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)
Beyond esterase-like activity of serum albumin. Histidine-(nitro) phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light
Kowacz M and Warszynski P
arXiv (2018)
Impact of diet on irinotecan toxicity in mice
Mallick P, et al.
Chemico-Biological Interactions, 291, 87-94 (2018)
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