推荐产品
产品名称
4-硝基苯基乙酸酯, esterase substrate
质量水平
方案
≥98% (TLC)
表单
powder or crystals
mp
75-77 °C (lit.)
储存温度
−20°C
SMILES字符串
CC(=O)Oc1ccc(cc1)[N+]([O-])=O
InChI
1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
InChI key
QAUUDNIGJSLPSX-UHFFFAOYSA-N
基因信息
human ... PON1(5444)
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应用
4-硝基苯基乙酸酯已用于：
- 评估人胚肾细胞系中的酯酶活性
- 碳酸酐酶抑制试验
- 通过牛血清白蛋白的酯酶活性，将其转换为 对硝基苯酚（p-NP）的研究中
- 作为确定小鼠肝细胞中羧酸酯酶（CES）活性的底物
- 研究磁性CLEAs基质中交联酶聚集体（CLEAs）和磁性氧化铁纳米粒子（MIONPs）的生物共轭优势
底物
生色酯酶底物。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
储存分类代码
5.1B - Oxidizing hazardous materials
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
个人防护装备
Eyeshields, Gloves, type N95 (US)
Michelle R Baker et al.
Biochemistry research international, 2011, 739712-739712 (2011-09-16)
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation. Susceptibility to chemical modification by methylglyoxal and
Novel Redox-Dependent Esterase Activity (EC 3.1.1.2) for DJ-1: Implications for Parkinson's Disease.
Emmanuel Vázquez-Mayorga et al.
International journal of molecular sciences, 17(8) (2016-08-25)
Mutations the in human DJ-1 (hDJ-1) gene are associated with early-onset autosomal recessive forms of Parkinson's disease (PD). hDJ-1/parkinsonism associated deglycase (PARK7) is a cytoprotective multi-functional protein that contains a conserved cysteine-protease domain. Given that cysteine-proteases can act on both
Immunomodulatory, antiglycation and anti-ulcerative properties of Ruellia squarrosa Fenzl Acanthaceae
Afzal K, et al.
Tropical Journal of Pharmaceutical Research, 16(8), 1751-1755 (2017)
Impact of diet on irinotecan toxicity in mice
Mallick P, et al.
Chemico-Biological Interactions, 291, 87-94 (2018)
Beyond esterase-like activity of serum albumin. Histidine-(nitro) phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light
Kowacz M and Warszynski P
arXiv (2018)
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