InChI
1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2
SMILES string
O=NN1CCOCC1
InChI key
ZKXDGKXYMTYWTB-UHFFFAOYSA-N
form
solid
Quality Level
Biochem/physiol Actions
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.
Packaging
散装
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
target_organs
Liver
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B - Muta. 2 - STOT RE 1
W Lijinsky et al.
Carcinogenesis, 3(8), 911-915 (1982-01-01)
A comparison was made of the carcinogenic effectiveness of some cyclic nitrosamines containing oxygen in the ring. The compounds were administered to F344 rats at approximately equimolar concentrations in drinking water. Nitrosomorpholine, nitroso-1,3-oxazolidine and nitrosotetrahydro-1,3-oxazine were of similar potency and
W Lijinsky et al.
In vivo (Athens, Greece), 5(2), 85-89 (1991-03-01)
A number of nitrosamines that have been studied by administration to rats as solutions in drinking water have been examined by gavage administration of similar doses, for assessment of the role of pharmacokinetics in organ-specific carcinogenesis. Methylnitrosoethylamine was more effective
Yong-Cang Wang et al.
Hepato-gastroenterology, 58(112), 2032-2035 (2012-01-12)
Concern that much controversy exists with respect to the role of estrogen in hepatocarcinogenesis prompted us to examine the effect of estrogen, at physiological concentrations, on our established HCC rat model induced by diethylnitrosamine and N-nitrosomorpholine. Female Sprague-Dawley rats were
Jutta Groos et al.
Mathematical biosciences, 202(2), 248-268 (2006-04-11)
Several hypotheses are established to describe the formation and progression of foci of altered hepatocytes (FAH). A common model of hepatocarcinogenesis is the mutation model (MM), which is based on the assumption that cells have to undergo multiple successive changes
D Slamenova et al.
Neoplasma, 55(4), 280-285 (2008-05-29)
N-nitrosomorpholine (NMOR) belongs to the group of N-nitrosamines and represents a known hepatocarcinogen. Exposure to this compound is considered to be a potential health hazard to humans. There is, however, considerable evidence that the effect of many carcinogenic agents can
商品
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持