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About This Item
经验公式（希尔记法）:
C4H8N2O2
CAS号:
分子量:
116.12
MDL编号:
UNSPSC代码:
41116105
PubChem化学物质编号:
NACRES:
NA.25
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表单
solid
质量水平
SMILES字符串
O=NN1CCOCC1
InChI
1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2
InChI key
ZKXDGKXYMTYWTB-UHFFFAOYSA-N
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生化/生理作用
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.
包装
散装
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Carc. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
W Lijinsky et al.
Carcinogenesis, 3(8), 911-915 (1982-01-01)
A comparison was made of the carcinogenic effectiveness of some cyclic nitrosamines containing oxygen in the ring. The compounds were administered to F344 rats at approximately equimolar concentrations in drinking water. Nitrosomorpholine, nitroso-1,3-oxazolidine and nitrosotetrahydro-1,3-oxazine were of similar potency and
N-Nitrosamines (15 listings): N-nitrosomorpholine.
Report on carcinogens : carcinogen profiles, 12, 319-320 (2011-08-24)
M Tatsuta et al.
Cancer letters, 119(1), 109-113 (2008-04-01)
The effects of prolonged administration of the diuretic amiloride on hepatocarcinogenesis induced by N-nitrosomorpholine (NNM) and the labeling index of the liver were investigated in male Sprague-Dawley rats. Rats were given drinking water containing NNM for 8 weeks and received
Wolf D Kuhlmann et al.
International journal of experimental pathology, 87(5), 343-359 (2006-09-13)
Adult hepatocytes and liver-cell progenitors play a role in restoring liver tissue after injury. For the study of progenitor cells in liver repair, experimental models included (a) surgical removal of liver tissue by partial hepatectomy; (b) acute injury by carbontetrachloride;
Jutta Groos et al.
Toxicological sciences : an official journal of the Society of Toxicology, 99(2), 446-454 (2007-07-20)
Within the scope of the Rat Liver Foci Bioassay the model carcinogens N-nitrosomorpholine (NNM), 2-acetylaminoflouren (2-AAF), phenobarbital (PB), and clofibrate (CF) were analyzed concerning their potency and dose-response relationship to induce foci of altered hepatocytes (FAHs), which are known to
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Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
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