N7251
4-硝基邻苯二酚硫酸盐 二钾盐
chromogenic sulphatase substrate, crystalline
别名:
2-羟基-5-硝基苯硫酸盐, 2-羟基-5-硝基苯硫酸盐 二钾盐 一水合物, 对硝基儿茶酚硫酸盐 二钾盐
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关于此项目
线性分子式:
C6H3NO7SK2
化学文摘社编号:
分子量:
311.35
Beilstein:
3805018
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
一般描述
4-硝基儿茶酚硫酸盐是一种芳香族硫酸盐。
显色硫酸酯酶底物。
应用
4-硝基儿茶酚硫酸二钾盐被用作粘多糖 VI（MPS VI）分析的底物。它也被用来测量糖胺聚糖（GAG）降解酶-芳基磺化酶B和外糖苷酶的活性。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
C O'Fagain et al.
The Biochemical journal, 201(2), 345-352 (1982-02-01)
A simple model is described to account for the anomalous time course of arylsulphatase A. In the case of the ox liver and human placental enzymes the enzyme-nitrocatechol sulphate complex can, in addition to forming products, slowly break down to
M Lee-Vaupel et al.
Clinica chimica acta; international journal of clinical chemistry, 164(2), 171-180 (1987-04-30)
Arylsulfatase A hydrolyzes the artificial chromogenic substrate 4-nitrocatechol-sulfate at 0 degree C at a rate of 24% of that at 37 degrees C whereas arylsulfatase B is almost inactive at 0 degree C. Based on this observation, a simple assay
Sandra Del Carmen Mendoza-Ruvalcaba et al.
Genetics and molecular biology, 43(1), e20180347-e20180347 (2020-02-28)
Mucopolysaccharidoses (MPS) are a group of genetic disorders, each resulting from the deficiency of one of the lysosomal enzymes that catabolizes mucopolysaccharides. For the accurate diagnosis of the disease, the quantification of a specific enzymatic activity is needed. In the
Camila M Adade et al.
Micron (Oxford, England : 1993), 38(3), 252-256 (2006-07-25)
Lysosomes of trypanosomatid protozoa are poorly known. In this work we have cytochemically detected the lysosomal enzyme aryl sulphatase in the trypanosomatids Trypanosoma cruzi and Crithidia fasciculata, by using p-nitrocatecholsulphate as substrate. Positive reaction was located exclusively inside membrane-bound cytoplasmic
Ilhem Barboura et al.
Diagnostic pathology, 7, 11-11 (2012-01-31)
Metachromatic leukodystrophy (MLD) is a recessive autosomal disease which is characterized by an accumulation of sulfatides in the central and peripheral nervous system. It is due to the enzyme deficiency of the sulfatide sulfatase i.e. arylsulfatase A (ASA). we studied
商品
Drug conjugate analysis and the enzymatic hydrolysis of glucuronides
实验方案
Enzymatic Assay of Sulfatase (EC 3.1.6.1.)
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