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Merck
CN

N6664

Sigma-Aldrich

神经连氮

≥98% (HPLC)

别名:

2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H imidazole

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About This Item

经验公式(希尔记法):
C27H21ClN2O3
分子量:
456.92
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
NACRES:
NA.25

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

yellow

溶解性

DMSO: >20 mg/mL

储存温度

−20°C

SMILES字符串

COc1ccc(cc1)-c2nc([nH]c2-c3ccc(OC)cc3)-c4ccc(o4)-c5cccc(Cl)c5

InChI

1S/C27H21ClN2O3/c1-31-21-10-6-17(7-11-21)25-26(18-8-12-22(32-2)13-9-18)30-27(29-25)24-15-14-23(33-24)19-4-3-5-20(28)16-19/h3-16H,1-2H3,(H,29,30)

InChI key

FEEOFPAEDSMOTO-UHFFFAOYSA-N

生化/生理作用

Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Dam. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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Jun Ding et al.
Journal of Alzheimer's disease : JAD, 37(3), 587-592 (2013-08-21)
Ciliary neurotrophic factor (CNTF) is a pleiotropic cytokine that has been fully studied for its structure, receptor, and signaling pathways and its multiplex effects on neural system, skeletal muscle, and weight control. Recent research demonstrates that CNTF also plays an
Ronald W Irwin et al.
Frontiers in endocrinology, 2, 117-117 (2011-01-01)
The proliferative pool and regenerative potential of neural stem cells diminishes with age, a phenomenon that may be exacerbated in prodromal and mild Alzheimer's disease (AD) brains. In parallel, the neuroactive progesterone metabolite, allopregnanolone (APα), along with a host of

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