N5538
单克隆抗-3-硝基酪氨酸 小鼠抗
clone 18G4, purified immunoglobulin, buffered aqueous glycerol solution
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
18G4, monoclonal
Application:
WB
Citations:
17
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
18G4, monoclonal
form
buffered aqueous glycerol solution
mol wt
antigen ~55 kDa
species reactivity
wide range
technique(s)
western blot: 1:1,000 using mouse and rat brain
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
nitration (Tyr)
Gene Information
human ... NOS1(4842)
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General description
3-硝基酪氨酸（3-NT）是通过在氧化和亚硝化胁迫下响应过氧亚硝基的产生，在酪氨酸残基的酚环的第三个位置引入硝基三原子团（-NO2）合成的。
单克隆抗3-硝基酪氨酸可识别大多数物种中的3-硝基酪氨酸。蛋白质酪氨酸硝化导致翻译后修饰，作为一氧化氮信号传导的重要组成部分，越来越受到关注。
Immunogen
3-硝基酪氨酸-KLH。
Application
小鼠单克隆抗3-硝基酪氨酸抗体可用于蛋白质印迹分析和免疫组织化学。
Biochem/physiol Actions
组织提取物中的3-硝基酪氨酸（3-NT）是测定过氧亚硝基诱导的蛋白质损伤的标志物。3-NT用作确定与各种疾病相关的蛋白质硝化的生物标志物。它与以内皮功能障碍为特征的疾病有关，例如中风、心肌梗塞、动脉粥样硬化和糖尿病。
Physical form
在20 mM磷酸钠、150 mM氯化钠、50%甘油和3 mM叠氮化钠中的溶液。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
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