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安全信息

安全和法规

N3288

(+)-Norfenfluramine 盐酸盐

Name: (+)-Norfenfluramine 盐酸盐
Brand: SIGMA

≥98% (HPLC), powder

别名:

JP 92, NSC 43036, S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine 盐酸盐

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About This Item

经验公式（希尔记法）:

C₁₀H₁₂F₃N · HCl

CAS号:

37936-89-3

分子量:

239.67

MDL编号:

MFCD11045299

UNSPSC代码:

12352116

PubChem化学物质编号:

329818604

NACRES:

NA.77

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质量水平

100

方案

≥98% (HPLC)

表单

powder

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

储存条件

desiccated

颜色

white

溶解性

H₂O: >10 mg/mL

储存温度

2-8°C

SMILES字符串

Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F

InChI

1S/C10H12F3N.ClH/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13;/h2-4,6-7H,5,14H2,1H3;1H/t7-;/m0./s1

InChI key

PIDLOFBRTWNFAR-FJXQXJEOSA-N

生化/生理作用

(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.