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经验公式(希尔记法):
C11H13NO7
化学文摘社编号:
分子量:
271.22
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
233-572-7
MDL number:
产品名称
4-Nitrophenyl α-D-xylopyranoside, α-xylosidase substrate
InChI key
MLJYKRYCCUGBBV-UHFFFAOYSA-N
InChI
1S/C11H13NO7/c13-8-5-18-11(10(15)9(8)14)19-7-3-1-6(2-4-7)12(16)17/h1-4,8-11,13-15H,5H2
SMILES string
OC1COC(Oc2ccc(cc2)N(=O)=O)C(O)C1O
assay
≥99% (HPLC)
form
powder
solubility
methanol: soluble 20 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
Quality Level
General description
Chromogenic substrate for α-xylosidase
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Talia Weinstein et al.
Connective tissue research, 53(2), 169-179 (2011-12-14)
The familial disease of hereditary multiple exostoses is characterized by abnormal skeletal deformities requiring extensive surgical procedures. In hereditary multiple exostoses patients there is a shortage in the pericellular glycosaminoglycan (GAG) of heparan sulfate (HS), related to defective activity of
M Gómez et al.
Biochimie, 83(10), 961-967 (2001-12-01)
The variation of kinetic parameters of beta-xylosidase from Trichoderma reesei QM 9414 with pH was used to elucidate the chemical mechanism of the p-nitrophenyl beta-D-xylopyranoside hydrolysis. The pH-dependence of V and V/K(m) showed that a group on the enzyme with
Masaki Yanagishita et al.
Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan, 73(1), 20-25 (2006-04-25)
Biosynthesis of proteoglycans and glycosaminoglycans in the presence of p-nitrophenyl-xyloside was studied using a primary rat ovarian granulosa cell culture system. Addition of p-nitrophenyl-xyloside into cell culture medium caused about a 700% increase of [³⁵S]sulfate incorporation (ED50 at 0.03 mM)
Fabiana Fonseca Zanoelo et al.
FEMS microbiology letters, 240(2), 137-143 (2004-11-04)
An inducible mycelial beta-glucosidase from Scytalidum thermophilum was characterized. The enzyme exhibited a pI of 6.5, a carbohydrate content of 15%, and an apparent molecular mass of about 40 kDa. Optima of temperature and pH were 60 degrees C and
Yvonne M Bastiaansen-Jenniskens et al.
Biochemical and biophysical research communications, 379(2), 222-226 (2008-12-23)
To understand cartilage degenerative diseases and improve repair procedures, we investigate the influence of glycosaminoglycans (GAGs) on cartilage matrix biochemistry and functionality. Bovine articular chondrocytes were cultured in alginate beads with(out) para-nitrophenyl-beta-d-xyloside (PNPX) to inhibit GAG incorporation into newly formed
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