跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

N1516

Sigma-Aldrich

2-O-(p-基苯基)-α-D-N-乙酰神经氨酸

chromogenic, ≥95%, powder

别名:

PNP-a-NeuNAc

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C17H22N2O11
CAS号:
26112-88-9
分子量:
430.36
MDL编号:
MFCD00132944
UNSPSC代码:
12352204
PubChem化学物质编号:
24897497
NACRES:
NA.32

产品名称

2-O-(p-基苯基)-α-D-N-乙酰神经氨酸, ≥95%

质量水平

200

方案

≥95%

表单

powder

杂质

~0.5% free p-nitrophenol

溶解性

methanol: 25 mg/mL, clear, colorless to faintly yellow

运输

wet ice

储存温度

−20°C

SMILES字符串

CC(=O)NC1C(O)CC(OC1C(O)C(O)CO)(Oc2ccc(cc2)N(=O)=O)C(O)=O

InChI

1S/C17H22N2O11/c1-8(21)18-13-11(22)6-17(16(25)26,30-15(13)14(24)12(23)7-20)29-10-4-2-9(3-5-10)19(27)28/h2-5,11-15,20,22-24H,6-7H2,1H3,(H,18,21)(H,25,26)

InChI key

OICUZSPXIJAAEA-UHFFFAOYSA-N

应用

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid may be used as a substrate to measure sialidase enzyme activity.

生化/生理作用

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid serves as a sialyl donor in enzyme-catalyzed trans-sialylation.

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
054K5009V
054K5009
035H5018
117H5115
114H5024

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Synthesis of p-nitrophenyl 5-acetamido-3,5-dideoxy-alpha-D-glycero-D-galacto-2-nonulopyranosid onic acid, a chromogenic substrate for sialidases.
V Eschenfelder et al.
Carbohydrate research, 162(2), 294-297 (1987-05-01)
Yao Guo et al.
Journal of biotechnology, 170, 60-67 (2013-12-03)
This study examined a recombinant Pasteurella multocida sialyltransferase exhibiting dual trans-sialidase activities. The enzyme catalyzed trans-sialylation using either 2-O-(p-nitrophenyl)-α-d-N-acetylneuraminic acid or casein glycomacropeptide (whey protein) as the sialyl donor and lactose as the acceptor, resulting in production of both 3'-sialyllactose
X Guo et al.
The Biochemical journal, 296 ( Pt 2), 291-292 (1993-12-01)
When the time course of the hydrolysis of identical solutions of p-nitrophenyl N-acetyl-alpha-D-neuraminide by Salmonella typhimurium neuraminidase is monitored by u.v. and by its optical rotation, the rotation change is synchronous with, or even marginally in advance of, the absorbance
Pascal Maurice et al.
Scientific reports, 6, 38363-38363 (2016-12-06)
Neuraminidase 1 (NEU1) is a lysosomal sialidase catalyzing the removal of terminal sialic acids from sialyloconjugates. A plasma membrane-bound NEU1 modulating a plethora of receptors by desialylation, has been consistently documented from the last ten years. Despite a growing interest
Bentley Lim et al.
Cell, 169(3), 547-558 (2017-04-22)
The gut microbiota is implicated in numerous aspects of health and disease, but dissecting these connections is challenging because genetic tools for gut anaerobes are limited. Inducible promoters are particularly valuable tools because these platforms allow real-time analysis of the

商品

Sialic Acid

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门