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Merck
CN

N1162

Sigma-Aldrich

NS3763

≥98% (HPLC), solid

别名:

5-Carboxy-2,4-dibenzamidobenzoic acid

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About This Item

经验公式(希尔记法):
C22H16N2O6
CAS号:
分子量:
404.37
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

方案

≥98% (HPLC)

表单

solid

颜色

off-white

溶解性

DMSO: ~24 mg/mL

储存温度

2-8°C

SMILES字符串

OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c3ccccc3

InChI

1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)

InChI key

UUDYZUDTQPLDDP-UHFFFAOYSA-N

生化/生理作用

First non-competitive antagonist of GluK5 receptor.

特点和优势

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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访问文档库

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Katherine Waters et al.
Developmental biology, 344(2), 1011-1025 (2010-07-06)
Proliferating germ cells in Caenorhabditiselegans provide a useful model system for deciphering fundamental mechanisms underlying the balance between proliferation and differentiation. Using gene expression profiling, we identified approximately 200 genes upregulated in the proliferating germ cells of C. elegans. Functional
Saravanapriah Nadarajan et al.
Development (Cambridge, England), 136(13), 2223-2234 (2009-06-09)
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PloS one, 4(10), e7450-e7450 (2009-10-15)
The germinal center kinases (GCK) constitute a large, highly conserved family of proteins that has been implicated in a wide variety of cellular processes including cell growth and proliferation, polarity, migration, and stress responses. Although diverse, these functions have been
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Molecular and cellular biology, 29(14), 3881-3893 (2009-05-06)
In Caenorhabditis elegans, the central cell-killing process is essentially controlled by the interplay of four apoptotic factors: EGL-1/BH3-only protein, CED-9/Bcl2, CED-4/Apaf1, and CED-3/caspase. In cells destined to die, EGL-1 binds to CED-9 and results in the release of CED-4 from

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