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药品控制
USDEA Schedule IIIN; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
技术
HPLC: suitable
gas chromatography (GC): suitable
包装形式
neat
储存温度
room temp
SMILES字符串
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CCC2=O
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-16H,2-9H2,1H3/t13-,14+,15+,16-,18-/m0/s1
InChI key
JRIZOGLBRPZBLQ-QXUSFIETSA-N
一般描述
19-Nor-4-androstene-3,17-dione is an anabolic steroid used in dietary food supplements.
应用
19-Nor-4-androstene-3,17-dione may be used as a reference standard in the determination of 19-nor-4-androstene-3,17-dione in dietary supplements using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
法规信息
新产品
D H Catlin et al.
JAMA, 284(20), 2618-2621 (2000-11-22)
Several anabolic steroids are sold over-the-counter (OTC) in the United States, and their production is not regulated by the US Food and Drug Administration. Reports have suggested that use of these supplements can cause positive urine test results for metabolites
Alberto Cassetta et al.
The Journal of steroid biochemistry and molecular biology, 171, 80-93 (2017-03-06)
Phytoestrogens are plant-derived compounds that functionally and structurally mimic mammalian estrogens. Phytoestrogens have broad inhibitory activities toward several steroidogenic enzymes, such as the 17β-hydroxysteroid dehydrogenases (17β-HSDs), which modulate the biological potency of androgens and estrogens in mammals. However, to date
Mario Thevis et al.
Therapeutic drug monitoring, 29(2), 236-247 (2007-04-10)
5alpha-Reductase inhibitors such as finasteride are prohibited in sports according to the World Anti-Doping Agency. This class of drugs is used therapeutically to treat benign prostatic hyperplasia, as well as male baldness, by decreasing 5alpha-reductase activity. Accordingly, metabolic pathways of
Phillip Watson et al.
Medicine and science in sports and exercise, 42(4), 754-761 (2009-12-03)
This study examined the influence of a supplement matrix on the excretion pattern of nandrolone metabolites in response to ingestion of a trace amount of 19-norandrostenedione. Ten male and nine female volunteers (mean ± SD: age = 26 ± 3
Phillip Watson et al.
Medicine and science in sports and exercise, 41(4), 766-772 (2009-03-12)
Quantities of various anabolic/androgenic steroids have been found in dietary supplements without their presence being disclosed on the label. The aim of this study was to quantify the excretion patterns of the diagnostic metabolites, 19-norandrosterone (19-NA), and 19-noretiocholanolone (19-NE) after
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