推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 38 kDa
种属反应性
human, mouse
浓度
1 mg/mL
技术
western blot: 0.5-1 μg/mL using a K562 cell lysate.
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... BNIP3L(665)
mouse ... Bnip3l(12177)
一般描述
BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L) is expressed in the outer membrane of mitochondria. The BNIP3L gene is localized on human chromosome 8p21.
免疫原
synthetic peptide corresponding to amino acids 77-92 of an internal domain of human Nix. This peptide is identical in mouse.
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化/生理作用
BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L) associates with proteins which are anti-apoptotic, like B-cell lymphoma 2 (Bcl-2). It also takes part in the growth of the erythroid lineage. Expression of BNIP3L is downregulated in lung cancer cells in vitro.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Ying-Qiang Shen et al.
Journal of pineal research, 64(3) (2017-12-17)
Head and neck squamous cell carcinoma (HNSCC) clearly involves activation of the Akt mammalian target of rapamycin (mTOR) signalling pathway. However, the effectiveness of treatment with the mTOR inhibitor rapamycin is often limited by chemoresistance. Melatonin suppresses neoplastic growth via
Ana Guerra-Librero et al.
Antioxidants (Basel, Switzerland), 10(4) (2021-05-01)
Metabolic reprogramming, which is characteristic of cancer cells that rapidly adapt to the hypoxic microenvironment and is crucial for tumor growth and metastasis, is recognized as one of the major mechanisms underlying therapeutic resistance. Mitochondria, which are directly involved in
Paul A Ney
Biochimica et biophysica acta, 1853(10 Pt B), 2775-2783 (2015-03-11)
Mitochondrial autophagy (mitophagy) is a core cellular activity. In this review, we consider mitophagy and related cellular processes and discuss their significance for human disease. Strong parallels exist between mitophagy and xenophagy employed in host defense. These mechanisms converge on
J J David Ho et al.
The Journal of biological chemistry, 287(34), 29003-29020 (2012-06-30)
The processes by which cells sense and respond to ambient oxygen concentration are fundamental to cell survival and function, and they commonly target gene regulatory events. To date, however, little is known about the link between the microRNA pathway and
M Matsushima et al.
Genes, chromosomes & cancer, 21(3), 230-235 (1998-04-02)
We have isolated a novel cDNA that encodes a product showing significant sequence homology (56% identity) to human NIP3, a protein thought to interact with adenovirus E1B19kD and human BCL2 proteins. This cDNA contains an open reading frame of 657
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