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Merck
CN

MSAB001

Sigma-Aldrich

SILuRich Anti-IL6 MAb, biotin conjugated

clone IL6-4G1, purified from hybridoma cell culture

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

mouse

质量水平

偶联物

biotin conjugate

抗体形式

purified from hybridoma cell culture

抗体产品类型

primary antibodies

克隆

IL6-4G1, monoclonal

表单

buffered aqueous solution

种属反应性

human

浓度

~1.0 mg/mL

技术

immunoblotting: suitable
immunoprecipitation (IP): 1-2 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells induced with IL 1β

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... IL6(3569)

相关类别

免疫原

Recombinant IL6

外形

Solution in 0.01 M phosphate buffered saline pH 7.4 containing 15 mM sodium azide

法律信息

SILu is a trademark of Sigma-Aldrich Co. LLC

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

Tove Boström et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1021, 3-13 (2015-11-14)
For protein analysis of biological samples, two major strategies are used today; mass spectrometry (MS) and antibody-based methods. Each strategy offers advantages and drawbacks. However, combining the two using an immunoenrichment step with MS analysis brings together the benefits of
Ailan Guo et al.
Molecular & cellular proteomics : MCP, 13(1), 372-387 (2013-10-17)
Protein methylation is a common posttranslational modification that mostly occurs on arginine and lysine residues. Arginine methylation has been reported to regulate RNA processing, gene transcription, DNA damage repair, protein translocation, and signal transduction. Lysine methylation is best known to
Regine M Schoenherr et al.
Proteomics, 16(15-16), 2141-2145 (2016-04-21)
Immunoaffinity enrichment of peptides coupled to multiple reaction monitoring-mass spectrometry (immuno-MRM) enables highly specific, sensitive, and precise quantification of peptides and post-translational modifications. Major obstacles to developing a large number of immuno-MRM assays are poor availability of monoclonal antibodies (mAbs)
Peter M Voorhees et al.
British journal of haematology, 161(3), 357-366 (2013-02-26)
Interleukin-6 (IL6) plays a central role in multiple myeloma pathogenesis and confers resistance to corticosteroid-induced apoptosis. We therefore evaluated the efficacy and safety of siltuximab, an anti-IL6 monoclonal antibody, alone and in combination with dexamethasone, for patients with relapsed or
L M Biasucci et al.
Circulation, 94(5), 874-877 (1996-09-01)
Elevated plasma levels of C-reactive protein have been found in the majority of patients with unstable angina. The evidence of elevated levels of acute-phase proteins in unstable angina is in line with a growing body of evidence that suggests that

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