产品名称
Alkaline Phosphatase (ALP) Assay Kit, sufficient for 100 fluorometric tests
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders
shipped in
wet ice
storage temp.
−20°C
Quality Level
Application
The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.
Biochem/physiol Actions
The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.
Features and Benefits
- Detection limit of 0.02 U/L
- Compatible with high-throughput handling systems.
General description
Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
存储类别
10 - Combustible liquids
wgk
WGK 1
相关内容
Instructions
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