推荐产品
检测方法
colorimetric
相关疾病
endocrinological disorders, diabetes; cancer
储存温度
−20°C
一般描述
乙酰乙酸（AcAc）是线粒体内通过两个乙酰辅酶 A 分子缩合而形成的 β-酮酸。AcAc 可以酶解为 3-羟基丁酸酯，也可以脱羧生成丙酮。在没有葡萄糖的情况下，酮体（AcAc、3-HB 和丙酮）被用作替代能源。在 I 型糖尿病、酒精中毒或饥饿中观察到过量的酮体。
适用性
适于测定血清、血浆、血液、尿液及其他体液样品中的乙酰乙酸浓度。
原理
乙酰乙酸检测试剂盒提供了一种简单而灵敏的程序来检测各种样品中的 AcAc（范围为 20-100 nmole/孔）。通过生成与存在的 AcAc 量成比例的比色（550 nm）产物来测定 AcAc 浓度。该试剂盒检测不到 3-羟基丁酸酯，并且对乙酰乙酸具有特异性。
仅试剂盒组分
产品编号
说明
- Acetoacetate Assay Buffer
- Acetoacetate Standard
- Acetoacetate Substrate
替代产品
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
10 - Combustible liquids
法规信息
新产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Anna Go et al.
Sensors (Basel, Switzerland), 21(14) (2021-07-25)
In this report, we present an enzyme deposited Au electrode for an electrochemical measurement of acetylacetic acid (AcAc) in urine. The electrode has an immobilized layer of a mixture of D-β-hydroxybutyrate dehydrogenase (HBDH) and nicotinamide adenine dinucleotide (NADH) as sensing
Tae Woong Whon et al.
EMBO reports, 22(1), e50663-e50663 (2020-11-24)
Castration of young males is widely used in the cattle industry to improve meat quality, but the mechanism linking hypogonadism and host metabolism is not clear. Here, we use metataxonomic and metabolomic approaches to evaluate the intestinal microbiota and host
Daniela Liśkiewicz et al.
Frontiers in cellular neuroscience, 15, 733607-733607 (2021-08-31)
Experimental and clinical data support the neuroprotective properties of the ketogenic diet and ketone bodies, but there is still a lot to discover to comprehensively understand the underlying mechanisms. Autophagy is a key mechanism for maintaining cell homeostasis, and therefore
Enrique Chávez et al.
The Journal of pharmacology and experimental therapeutics, 361(2), 292-302 (2017-02-18)
Background: Mitochondrion is an important metabolic and energetic organelle that regulates several cellular processes. Mitochondrial dysfunction has been related to liver diseases including hepatocellular carcinoma. As a result, the energetic demand is not properly supplied and mitochondrial morphologic changes have
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