产品名称
琥珀酸脱氢酶检测试剂盒, Sufficient for 100 Colorimetric tests
detection method
colorimetric
relevant disease(s)
neurological disorders
storage temp.
−20°C
Gene Information
human ... SDHA(6389), SDHAF1(644096), SDHAF2(54949), SDHB(6390), SDHC(6391), SDHD(6392)
mouse ... SDHA(66945), SDHAF1(68332), SDHAF2(66072), SDHB(67680), SDHC(66052), SDHD(66925)
rat ... SDHA(157074), SDHAF2(361726), SDHB(298596), SDHC(289217), SDHD(363061)
Application
本试剂盒适于检测不同生物样品（如细胞、组织培养上清液和纯化的线粒体）中琥珀酰脱氢酶的活性。
琥珀酸脱氢酶活性比色测定试剂盒已用于测定样品中琥珀酸脱氢酶的酶活性。
Biochem/physiol Actions
琥珀酸脱氢酶活性比色检测试剂盒为测定多种组织、细胞和分离线粒体中的 SDH 活性提供了一种简单、灵敏的程序。通过产生与存在的酶活性成比例的 600nm 吸光度的产物来确定 SDH 活性。一个单位的 SDH 是在 pH7.2，25℃ 下每分钟产生 1.0μmole DCIP 的酶量。
General description
琥珀酸脱氢酶（SDH；酶代码 EC 1.3.5.1）是一种线粒体酶，在真核生物和细菌中催化琥珀酸氧化为延胡索酸，并携带电子从 FADH 到 CoQ。在通过三羧酸循环和电子传递链维持细胞能量代谢中起中心作用。SDH 突变引起遗传性副神经节瘤/嗜铬细胞瘤综合征和一种被称为 Leigh 综合征的神经退行性疾病。
存储类别
10 - Combustible liquids
法规信息
常规特殊物品
此项目有
Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase.
Qi B and Han M
Cell (2018)
Mohammad Golam Sabbir et al.
Cell communication and signaling : CCS, 19(1), 98-98 (2021-09-27)
The calcium (Ca2+)/calmodulin (CAM)-activated kinase kinase 2 (CAMKK2)-signaling regulates several physiological processes, for example, glucose metabolism and energy homeostasis, underlying the pathogenesis of metabolic diseases. CAMKK2 exerts its biological function through several downstream kinases, therefore, it is expected that depending
Brian P Daniels et al.
Immunity, 50(1), 64-76 (2019-01-13)
As long-lived post-mitotic cells, neurons employ unique strategies to resist pathogen infection while preserving cellular function. Here, using a murine model of Zika virus (ZIKV) infection, we identified an innate immune pathway that restricts ZIKV replication in neurons and is
Fabrizio Pin et al.
Journal of cachexia, sarcopenia and muscle, 9(4), 685-700 (2018-07-17)
Cachexia frequently occurs in women with advanced ovarian cancer (OC), along with enhanced inflammation. Despite being responsible for one third of all cancer deaths, cachexia is generally under-studied in OC due to a limited number of pre-clinical animal models. We
Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia.
Pin F, et al.
Journal of Cachexia, Sarcopenia and Muscle, 9(4), 685-700 (2018)
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持