产品名称
自噬检测试剂盒, sufficient for 200 fluorometric tests
usage
sufficient for 200 fluorometric tests
detection method
fluorometric
relevant disease(s)
cancer; immunological diseases
storage temp.
−20°C
Biochem/physiol Actions
自噬检测试剂盒提供了一种简单直接的方法，使用专有的荧光自噬体标记物（λex = 333 /λem = 518nm）对多种细胞类型的自噬进行测定。
Application
- 熊果酸对肾癌细胞增殖、迁移的抑制作用及机制。：本研究探索了熊果酸对肾癌细胞增殖和迁移的抑制作用。自噬测定试剂盒可以证明熊果酸诱导自噬，导致细胞活力和迁移降低。这些发现强调了熊果酸通过调节自噬作为肾癌治疗剂的潜力（Lyu et al., 2022）。
本试剂盒适用于荧光显微镜和荧光微板分析仪检测哺乳动物细胞的自噬情况。
General description
自噬是一种进化上保守的降解过程，其降解目标为长寿命蛋白质、细胞器和其他细胞质成分，其通过溶酶体途径进行降解。多重细胞作用需要激活自噬途径，包括饥饿期间的存活、细胞内组分的清除、发育、以及免疫。
存储类别
10 - Combustible liquids
wgk
WGK 2
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