用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
endocrinological disorders, diabetes; neurological disorders
储存温度
−20°C
基因信息
human ... GAA(2548)
mouse ... GAA(14387)
rat ... GAA(367562)
一般描述
α-葡萄糖苷酶作用于末端非还原a(1→4)-连接D-葡萄糖残基，水解糖水化合物，释放D-葡萄糖。庞佩氏症和糖尿病会出现葡萄糖苷酶异常。
应用
α葡萄糖苷酶活性分析是结合被用来检测a-葡萄糖苷酶活性。
特点和优势
兼容高通量的操作系统。
适用性
适用于测定生物样品中的α-葡萄糖苷酶活性。
原理
在本检测中，α-葡糖苷酶活性通过α-葡糖苷酶水解 对硝基苯基-α-D吡喃葡萄糖苷的反应确定，该反应形成比色(405 nm)产物，与存在的α-葡糖苷酶活性成比例。
储存分类代码
10 - Combustible liquids
法规信息
监管及禁止进口产品
Anika E Wagner et al.
Oncotarget, 6(31), 30568-30578 (2015-09-17)
In this study, we tested whether a standardized epigallocatechin-3-gallate (EGCG) rich green tea extract (comprising > 90% EGCG) affects fitness and lifespan as well as parameters of glucose metabolism and energy homeostasis in the fruit fly, Drosophila melanogaster. Following the
Atta-ur-Rahman.
Studies in Natural Products Chemistry, Volume 37 (2017)
Inhibitory effect of rhubarb on intestinal a-glucosidase activity in type 1 diabetic rats.
Hou K J, et al.
Tropical Journal of Pharmaceutical Research, 16(6), 1293-1297 (2017)
Youngse Oh et al.
Molecules (Basel, Switzerland), 26(2) (2021-01-16)
Catalpa pod has been used in traditional medicine for the treatment of diabetes mellitus in South America. Studies on the constituents of Catalpa species have shown that it is rich in iridoids. In the present study, three previously undescribed compounds
Structure of human lysosomal acid a-glucosidase?a guide for the treatment of Pompe disease.
Veronique R Z, et al.
Nature Communications, 8(1), 1111-1111 (2017)
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