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用途
sufficient for 100 tests (Ultraviolet)
检测方法
colorimetric
相关疾病
cardiovascular diseases; genitourinary disorders; aging/geriatric diseases; orthopedic diseases
运输
dry ice
储存温度
−20°C
基因信息
human ... CKB(1152) , CKM(1158)
mouse ... CKB(12709) , CKM(12715)
rat ... CKB(24264) , CKM(24265)
一般描述
肌酸激酶（CK），又称磷酸肌酸激酶，是催化一个磷酸基团从ATP转移到肌酸，产生磷酸肌酸的酶，磷酸肌酸是肌肉和脑组织的重要能量储备。CK是一种由B（大脑）和M（肌肉）亚基组成的二聚体蛋白。现已发现三种同工酶，即：CK-MM、CK-MB和CK-BB。在心肌梗塞、横纹肌溶解、肌营养不良和肾功能衰竭等各种病理状况下，CK水平升高。
特点和优势
兼容高通量的操作系统。
适用性
适用于检测各种样品中（如血清和血浆）的肌酸激酶活性。本试剂盒可用于研究各种化合物对肌酸激酶活性的影响。
原理
通过偶联酶反应确定肌酸激酶活性，在340 nm处测量反应产生的NADPH，结果与样品中的CK活性成比例。在此反应中，磷酸肌酸和ADP转化为肌酸和ATP。己糖激酶将产生的ATP用于磷酸化葡萄糖，生成葡萄糖-6-磷酸；在葡萄糖-6-磷酸脱氢酶存在的情况下，NADP氧化葡萄糖-6-磷酸，生成NADPH和6-磷酸-D-葡萄糖酸。一个单位的CK指pH 6.0时，每分钟将1.0μmole磷酸盐从磷酸肌酸转移到ADP的酶量。 该试剂盒的线性范围为30-1,800 单位/L CK活性。
相关产品
警示用语：
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
储存分类代码
12 - Non Combustible Liquids
法规信息
常规特殊物品
含少量动物源组分生物产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy
Sinadinos A
PLoS Medicine null
Gary R Hunter et al.
Medicine and science in sports and exercise, 49(12), 2414-2421 (2017-07-25)
Resting energy expenditure (REE) increases after an intense exercise; however, little is known concerning mechanisms. The purpose of this study was to determine effects of a single bout of moderate-intensity continuous (MIC) aerobic exercise, or high-intensity interval (HII) exercise on
Christopher W Bach et al.
European journal of applied physiology, 117(5), 913-919 (2017-03-18)
To investigate the blood glucose kinetics and physiological effects experienced by a type 1 diabetic (T1D) finisher of a 3-day, multi-stage ultra endurance triathlon consisting of a 10 km swim and 144.8 km bike (stage 1), a 275.4 km bike (stage 2), and
Jill R Nelson et al.
Poultry science, 99(7), 3312-3318 (2020-07-04)
This study aimed to elucidate the mechanism by which adding Saccharomyces cerevisiae-derived yeast fermentate to the feed (XPC) or drinking water reduces stress in poultry. Day-old male Cobb 500 broiler chicks were assigned to 1 of 3 treatments: stressed control
HANAC Col4a1 Mutation in Mice Leads to Skeletal Muscle Alterations due to a Primary Vascular Defect
Guiraud S, et al.
The American Journal of Pathology, 505-516 null
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