产品名称
肌酸激酶活性检测试剂盒, sufficient for 100 tests (Ultraviolet)
usage
sufficient for 100 tests (Ultraviolet)
detection method
colorimetric
relevant disease(s)
cardiovascular diseases; genitourinary disorders; aging/geriatric diseases; orthopedic diseases
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... CKB(1152), CKM(1158)
mouse ... CKB(12709), CKM(12715)
rat ... CKB(24264), CKM(24265)
Application
适用于检测各种样品中（如血清和血浆）的肌酸激酶活性。本试剂盒可用于研究各种化合物对肌酸激酶活性的影响。
Biochem/physiol Actions
通过偶联酶反应确定肌酸激酶活性，在340 nm处测量反应产生的NADPH，结果与样品中的CK活性成比例。在此反应中，磷酸肌酸和ADP转化为肌酸和ATP。己糖激酶将产生的ATP用于磷酸化葡萄糖，生成葡萄糖-6-磷酸；在葡萄糖-6-磷酸脱氢酶存在的情况下，NADP氧化葡萄糖-6-磷酸，生成NADPH和6-磷酸-D-葡萄糖酸。一个单位的CK指pH 6.0时，每分钟将1.0μmole磷酸盐从磷酸肌酸转移到ADP的酶量。 该试剂盒的线性范围为30-1,800 单位/L CK活性。
Features and Benefits
兼容高通量的操作系统。
General description
肌酸激酶（CK），又称磷酸肌酸激酶，是催化一个磷酸基团从ATP转移到肌酸，产生磷酸肌酸的酶，磷酸肌酸是肌肉和脑组织的重要能量储备。CK是一种由B（大脑）和M（肌肉）亚基组成的二聚体蛋白。现已发现三种同工酶，即：CK-MM、CK-MB和CK-BB。在心肌梗塞、横纹肌溶解、肌营养不良和肾功能衰竭等各种病理状况下，CK水平升高。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
12 - Non Combustible Liquids
法规信息
常规特殊物品
含少量动物源组分生物产品
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