产品名称
脂蛋白脂肪酶（LPL）活性检测试剂盒, Supplied by Roar Biomedical, Inc.
usage
sufficient for 100 fluorometric tests
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
gastrointestinal diseases; cardiovascular diseases
storage temp.
2-8°C
Gene Information
human ... LPL(4023)
Analysis Note
Application
LPL 活性检测试剂盒可用于高甘油三酯血症患者血浆样本中 LPL 活性的检测。
适用于多种组织样品中脂蛋白脂肪酶活性的测定
Biochem/physiol Actions
LPL 活性检测试剂盒包括一种非荧光底物乳剂，在与 LPL 和预水解底物相互作用后变成强荧光，其可用作标准品，将荧光强度读数转换为形成的反应物的摩尔数（λEx = 370 nm/λEm= 450 nm）。该试验对 LPL 无特异性，还可检测肝脂酶活性。
General description
脂蛋白脂酶 (LPL) 水解与 VLDL 相关的甘油三酯。
存储类别
10 - Combustible liquids
Compound but non-linked heterozygous p. W14X and p. L279 V LPL gene mutations in a Chinese patient with long-term severe hypertriglyceridemia and recurrent acute pancreatitis.
Li X, et al.
Lipids in Health and Disease, 17(1), 144-144 (2018)
Xiaoyao Li et al.
Lipids in health and disease, 17(1), 144-144 (2018-06-21)
Variants in the lipoprotein lipase (LPL), apolipoprotein C-II (APOC2), apolipoprotein A-V (APOA5), GPIHBP1 and LMF1 genes may cause severe hypertriglyceridemia (HTG), which is now the second-leading aetiology of acute pancreatitis in China. The patient and his family were assessed for
Ismayil Tasdelen et al.
PloS one, 8(5), e64284-e64284 (2013-05-23)
The transcription factor PPARγ is the key regulator of adipocyte differentiation, function and maintenance, and the cellular target of the insulin-sensitizing thiazolidinediones. Identification and functional characterization of genes regulated by PPARγ will therefore lead to a better understanding of adipocyte
Chaofeng Yang et al.
Nutrition & metabolism, 9(1), 94-94 (2012-10-31)
Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepatocytes where FGFR1 is not significant. Both FGF19 and FGF21
Evemie Dubé et al.
Biology of reproduction, 88(1), 16-16 (2012-12-12)
Gestational diabetes mellitus (GDM) is a common complication of pregnancy that is characterized by glucose intolerance, leads to dyslipidemia, and is aggravated by obesity. Cholesterol is taken up by the placenta as part of lipoproteins through the scavenger receptor class
实验方案
Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.
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