用途
sufficient for 100 fluorometric tests
检测方法
fluorometric
相关疾病
cancer; cardiovascular diseases; hematological disorder
储存温度
−20°C
基因信息
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
一般描述
髓过氧化物酶(MPO)是一种含血红素的酶,催化氢过氧化物酶介导的卤离子氧化为次卤酸。髓过氧化物酶是一种在中性粒细胞中高度表达的溶酶体蛋白,其在由中性粒细胞刺激引起的抗微生物作用中起作用。髓过氧化物酶的作用也可能有助于心血管疾病的发生和发病。
应用
髓过氧化物酶 (MPO) 活性测定试剂盒用于测定髓过氧化物酶 (MPO) 活性。
适用性
适用于组织、细胞、血清和白细胞等生物样本中髓过氧化物酶 (MPO) 的测定
原理
MPO活性荧光测定试剂盒提供了一种简单、直接的方法,用于测量各种样品中的MPO 活性。在该测定中,MPO 催化次氯酸的形成,次氯酸与氨基苯基荧光素底物反应形成荧光素)牛磺酸氯胺。(λex = 485/λem = 525 nm)。一个单位的 MPO 是在室温下,每分钟水解 MPO 底物以产生 1.0 μmole 的荧光素的酶量。
警示用语:
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
储存分类代码
10 - Combustible liquids
法规信息
常规特殊物品
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