用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
cancer; cardiovascular diseases; hematological disorder
储存温度
−20°C
基因信息
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
一般描述
髓过氧化物酶（MPO）是一种含血红素的酶，催化氢过氧化物酶介导的卤离子氧化为次氯酸。髓过氧化物酶是一种在中性粒细胞中高度表达的溶酶体蛋白，其在由中性粒细胞刺激引起的抗微生物作用中起作用。髓过氧化物酶的作用也可能有助于心血管疾病的发生和发病。
应用
髓过氧化物酶比色活性测定试剂盒已用于测定样品中髓过氧化物酶的活性。
特点和优势
兼容高通量处理系统。
适用性
适用于组织、细胞、血清和白细胞等生物样本中髓过氧化物酶 (MPO) 的测定
原理
在该测定中，髓过氧化物酶催化次氯酸的形成，次氯酸与牛磺酸反应形成牛磺酸氯胺。牛磺酸氯胺与发色团 TNB 反应，形成无色产物 DTNB。一个单位的髓过氧化物酶活性定义为在 25℃ 下，每分钟水解底物并产生牛磺酸氯胺以消耗 1.0 μmole TNB的酶量。
警示用语：
Danger
危险分类
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
10 - Combustible liquids
闪点(°F)
188.6 °F
闪点(°C)
87 °C
法规信息
常规特殊物品
Yannan Liu et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(5), G550-G563 (2014-07-19)
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