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用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
cancer
储存温度
−20°C
一般描述
富马酸是琥珀酸脱氢酶氧化琥珀酸形成的三羧酸(TCA)循环中间体。在哺乳动物肝脏中，富马酸盐也是尿素循环的产物，其在细胞质中的释放导致其转化为苹果酸盐，随后转化成草酰乙酸盐，同时在细胞质中生成 NADH。富马酸盐水合酶的缺乏与富马酸盐的细胞浓度增加和肾细胞癌的发病率升高有关。这很可能是由富马酸盐介导的 HIF1 上调引起的。Fumarate 检测试剂盒是灵敏地检测各种样品中富马酸的便利的工具。
应用
Fumarate 检测试剂盒已用于测定样品中富马酸的浓度。
适用性
适用于检测各种样品中的富马酸盐，包括组织、细胞和血清
原理
通过酶测定法测定富马酸盐，其产生与存在的富马酸盐成比例的比色（450nm）产物。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
法规信息
常规特殊物品
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