用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
endocrinological disorders, diabetes; cancer; gastrointestinal diseases
储存温度
−20°C
一般描述
β-羟基丁酸盐，也称为3-羟基丁酸盐，是一种酮体，主要由脂肪酸氧化在肝脏中合成。当血糖水平下降时，酮体形成，即生酮作用，会升高。中度升高的血酮体通常发生在禁食和长期运动期间。在酒精或糖尿病酮症酸中毒期间，血液中的β-羟基丁酸盐会上升到异常高的水平。β-羟基丁酸盐可用作肝脏能量代谢的标记物。β-羟基丁酸盐的形成随着乙酰辅酶A的过量而增加，并作为大脑的能量来源。
应用
β-羟基丁酸盐检测试剂盒已用于
- 量化血浆/血清中的β-羟基丁酸盐水平
- 通过测定血浆酮体水平，研究延长生酮饮食后心肌18F-FDG摄取的变化
- 研究β-羟基丁酸盐在治疗脊髓损伤小鼠的损伤和神经病理性疼痛方面的作用
适用性
适合测量生物样本（包括血清和尿液）中的β-羟基丁酸盐水平
原理
在这个检测中，β-羟基丁酸盐浓度由偶联酶反应确定，这产生比色（450 nm）产物，与存在的β-羟基丁酸盐成比例。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
监管及禁止进口产品
Johanna Karlsson et al.
Journal of dairy science, 103(10), 8922-8937 (2020-08-05)
Ruminants can produce meat and milk from fibrous feed and byproducts not suitable for human consumption. However, high-yielding dairy cows are generally fed a high proportion of cereal grain and pulses, which could be consumed directly by humans. If high
Jiao Qian et al.
British journal of pharmacology, 174(13), 1961-1971 (2017-03-21)
Spinal cord injury (SCI) leads to severe motor and sensory dysfunction and significantly reduces the quality of life. The aim of the present work was to investigate the effect of administration of exogenous D-β-hydroxybutyrate (DBHB) on functional recovery and neuropathic
Adriana Lelis Carvalho et al.
Journal of cellular physiology, 233(2), 1585-1600 (2017-06-21)
There is a growing and alarming prevalence of obesity and the metabolic syndrome in type I diabetic patients (T1DM), particularly in adolescence. In general, low bone mass, higher fracture risk, and increased marrow adipose tissue (MAT) are features of diabetic
Alexandra Clément et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 27(2), 612-618 (2018-08-22)
Short periods of fasting and/or low-carbohydrate diet have been proven beneficial for decreasing the myocardial uptake of 18F-fluorodeoxyglucose (18F-FDG) and enhancing the detection of inflammatory heart diseases by 18F-FDG positron emission tomography (PET). This study aimed at determining whether this
A 1-week extension of a ketogenic diet provides a further decrease in myocardial 18 F-FDG uptake and a high detectability of myocarditis with FDG-PET.
Clement A, et al.
Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology, 1-7 (2018)
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