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用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
endocrinological disorders, diabetes; cancer; gastrointestinal diseases
储存温度
−20°C
一般描述
β-羟基丁酸盐，也称为3-羟基丁酸盐，是一种酮体，主要由脂肪酸氧化在肝脏中合成。当血糖水平下降时，酮体形成，即生酮作用，会升高。中度升高的血酮体通常发生在禁食和长期运动期间。在酒精或糖尿病酮症酸中毒期间，血液中的β-羟基丁酸盐会上升到异常高的水平。β-羟基丁酸盐可用作肝脏能量代谢的标记物。β-羟基丁酸盐的形成随着乙酰辅酶A的过量而增加，并作为大脑的能量来源。
应用
β-羟基丁酸盐检测试剂盒已用于
- 量化血浆/血清中的β-羟基丁酸盐水平
- 通过测定血浆酮体水平，研究延长生酮饮食后心肌18F-FDG摄取的变化
- 研究β-羟基丁酸盐在治疗脊髓损伤小鼠的损伤和神经病理性疼痛方面的作用
适用性
适合测量生物样本（包括血清和尿液）中的β-羟基丁酸盐水平
原理
在这个检测中，β-羟基丁酸盐浓度由偶联酶反应确定，这产生比色（450 nm）产物，与存在的β-羟基丁酸盐成比例。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
监管及禁止进口产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Yongsheng Yu et al.
European journal of pharmacology, 829, 121-128 (2018-04-22)
The present study was designed to examine the protection of D-β-hydroxybutyrate (BHB) against ischemia/reperfusion (I/R) injury in heart and investigate its underlying mechanism. Male adult mice were exposed to 30 min of ischemia and 24 h of reperfusion. Osmotic pumps were implanted
Jenni Määttä et al.
Scientific reports, 8(1), 13583-13583 (2018-09-13)
Hypoxia of residence at high altitude (>2500 m) decreases birth weight. Lower birth weight associates with infant mortality and morbidity and increased susceptibility to later-in-life cardiovascular and metabolic diseases. We sought to determine the effects of hypoxia on maternal glucose and
Tumor metabolism, the ketogenic diet and β-hydroxybutyrate: novel approaches to adjuvant brain tumor therapy
Woolf E C, et al.
Frontiers in Molecular Neuroscience, 9, 122-122 (2016)
Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training.
Knudsen J G, et al.
Physiological Reports, 4(9), e12788-e12788 (2016)
Yongsheng Lan et al.
PloS one, 13(10), e0205562-e0205562 (2018-10-12)
Aerobic exercise improves cognitive function and adult hippocampal neurogenesis. However, the effects of aerobic exercise combined with strength exercise on cognitive function and adult hippocampal neurogenesis are still unknown. In this study, we established exercise paradigms in rats to mimic
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