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用途
sufficient for 100 colorimetric tests
检测方法
colorimetric
相关疾病
cancer
运输
dry ice
储存温度
−70°C
一般描述
烟酰胺腺嘌呤二核苷酸磷酸（NADP）是参与许多氧化还原反应的酶促辅因子，其在还原（NADPH）和氧化（NADP）形式之间循环。NADP 还参与生物合成反应，例如脂质和核酸合成，其中它起还原剂的作用。戊糖磷酸途径（PPP）的氧化分支是动物细胞中产生的 NADPH 的主要来源。
应用
NADP/NADPH（烟酰胺腺嘌呤二核苷酸磷酸）定量试剂盒已用于定量 NADP/NADPH。它已被用于量化 NAD（P）H ，以确定 SHMT2（丝氨酸羟甲基转移酶 2）特异性酶活性。
适用性
适用于检测细胞和组织裂解物等多种生物样本中的NADP、NADPH及其比值
原理
NADP/NADPH 定量试剂盒为细胞内核苷酸、NADP（烟酰胺腺嘌呤二核苷酸磷酸）和 NADPH 及其比例的灵敏检测提供了便利的工具。不需要从样品中纯化 NADP/NADPH。该测定法对 NADP 和 NADPH 具有特异性，并且不检测 NAD 或 NADH。NADPt（NADP 和 NADPH）或 NADPH 在比色测定（450nm）中定量。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Luigi Mele et al.
Cell death & disease, 9(5), 572-572 (2018-05-16)
Pentose phosphate pathway (PPP) is a major glucose metabolism pathway, which has a fundamental role in cancer growth and metastasis. Even though PPP blockade has been pointed out as a very promising strategy against cancer, effective anti-PPP agents are not
Mechanisms of action of isoniazid.
Timmins G S and Vojo D
Molecular Microbiology, 62(5), 1220-1227 (2006)
Andreas Carstensen et al.
Plant physiology, 177(1), 271-284 (2018-03-16)
Phosphorus (P) is an essential macronutrient, and P deficiency limits plant productivity. Recent work showed that P deficiency affects electron transport to photosystem I (PSI), but the underlying mechanisms are unknown. Here, we present a comprehensive biological model describing how
Q Shi et al.
Toxicology, 381, 64-74 (2017-02-28)
It has been well established that inflammation and concurrent mutagenic exposures drive the carcinogenic process in a synergistic way. To elucidate the role of the inflammatory cytokine IL-8 in this process, we studied its effect on the activation and deactivation
Metabolic engineering of Escherichia coli: increase of NADH availability by overexpressing an NAD+-dependent formate dehydrogenase.
Berri'os-Rivera S J, et al.
Metabolic engineering, 4(3), 217-229 (2002)
商品
Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.
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