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Merck
CN

MAK038

Sigma-Aldrich

NADP/NADPH定量检测试剂盒

sufficient for 100 colorimetric tests

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别名:
NADP/NADPH检测试剂盒
UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.25

用途

sufficient for 100 colorimetric tests

检测方法

colorimetric

相关疾病

cancer

运输

dry ice

储存温度

−70°C

一般描述

烟酰胺腺嘌呤二核苷酸磷酸(NADP)是参与许多氧化还原反应的酶促辅因子,其在还原(NADPH)和氧化(NADP)形式之间循环。NADP 还参与生物合成反应,例如脂质和核酸合成,其中它起还原剂的作用。戊糖磷酸途径(PPP)的氧化分支是动物细胞中产生的 NADPH 的主要来源。

应用

NADP/NADPH(烟酰胺腺嘌呤二核苷酸磷酸)定量试剂盒已用于定量 NADP/NADPH。它已被用于量化 NAD(P)H ,以确定 SHMT2(丝氨酸羟甲基转移酶 2)特异性酶活性。

适用性

适用于检测细胞和组织裂解物等多种生物样本中的NADP、NADPH及其比值

原理

NADP/NADPH 定量试剂盒为细胞内核苷酸、NADP(烟酰胺腺嘌呤二核苷酸磷酸)和 NADPH 及其比例的灵敏检测提供了便利的工具。不需要从样品中纯化 NADP/NADPH。该测定法对 NADP 和 NADPH 具有特异性,并且不检测 NAD 或 NADH。NADPt(NADP 和 NADPH)或 NADPH 在比色测定(450nm)中定量。

替代产品

象形图

Health hazardCorrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

WGK

WGK 3

法规信息

常规特殊物品

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Andreas Carstensen et al.
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Phosphorus (P) is an essential macronutrient, and P deficiency limits plant productivity. Recent work showed that P deficiency affects electron transport to photosystem I (PSI), but the underlying mechanisms are unknown. Here, we present a comprehensive biological model describing how
Luigi Mele et al.
Cell death & disease, 9(5), 572-572 (2018-05-16)
Pentose phosphate pathway (PPP) is a major glucose metabolism pathway, which has a fundamental role in cancer growth and metastasis. Even though PPP blockade has been pointed out as a very promising strategy against cancer, effective anti-PPP agents are not
Q Shi et al.
Toxicology, 381, 64-74 (2017-02-28)
It has been well established that inflammation and concurrent mutagenic exposures drive the carcinogenic process in a synergistic way. To elucidate the role of the inflammatory cytokine IL-8 in this process, we studied its effect on the activation and deactivation
Mechanisms of action of isoniazid.
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Metabolic engineering of Escherichia coli: increase of NADH availability by overexpressing an NAD+-dependent formate dehydrogenase.
Berri'os-Rivera S J, et al.
Metabolic engineering, 4(3), 217-229 (2002)

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