产品名称
果糖-6-磷酸检测试剂盒, sufficient for 100 fluorometric tests
usage
sufficient for 100 fluorometric tests
detection method
fluorometric
relevant disease(s)
cancer
storage temp.
−20°C
Application
果糖-6-磷酸测定试剂盒已被用于测定果糖-6-磷酸（F-6-P） 和葡萄糖-6-磷酸（G6P）。
适用于对多种样品中的果糖-6-磷酸进行定量
Biochem/physiol Actions
果糖-6-磷酸的浓度可通过偶联酶反应进行测定，该反应可产生荧光测定产物（λex = 535nm /λem = 587nm），其与存在的果糖-6-磷酸成比例。该试剂盒的一般灵敏度为0.01至0.5纳摩尔F6P。
General description
果糖-6-磷酸（F6P）是一种通过磷酸葡萄糖异构酶异构化葡萄糖-6-磷酸产生的糖酵解途径中间体。F6P可被进一步磷酸化为果糖1,6-二磷酸，随后可裂解为磷酸甘油醛和磷酸二羟丙酮。F6P也可以从糖酵解分流至磷酸戊糖途径的非氧化分支，以生成用于核苷酸合成的戊糖磷酸。F6P水平在快速增殖的细胞（如癌细胞）中升高。果糖-6-磷酸测定试剂盒是一种高灵敏度和简单的基于荧光的方法，可用于对多种样品中的F6P进行定量。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
10 - Combustible liquids
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
法规信息
低风险生物材料
常规特殊物品
此项目有
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Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。
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