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Merck
CN

M9557

Sigma-Aldrich

Anti-Macrophage Inflammatory Protein-3β antibody produced in goat

affinity isolated antibody, lyophilized powder

别名:

Anti-MIP-3β

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

mouse

技术

immunocytochemistry: 5-15 μg/mL
neutralization: 0.8-4 μg/mL
western blot: 0.1-0.2 μg/mL

UniProt登记号

储存温度

−20°C

基因信息

mouse ... Ccl19(24047)

一般描述

The antibody neutralizes the biological activity of recombinant mouse MIP-3β. Using 50 times more, the antibody will neutralize the biological activity of recombinant human MIP-3β. The antibody shows 5% cross-reactivity with recombinant human MIP-3β.

免疫原

Recombinant mouse MIP-3β, expressed in Escherichia coli.

生化/生理作用

Macrophage Inflammatory Protein-3β is a chemokine that facilitates the migration of dendritic cells and antigen-presenting cells. It interacts with specific G protein-coupled seven-transmembrane domain chemokine receptor, CCR7 and promotes interactions between T cells and dendritic cells and migration of activated B cells to lymphoid tissues.

外形

Lyophilized from a 0.2 μm-filtered solution in phosphate-buffered saline containing carbohydrates.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jian-mei Hou et al.
Acta pharmacologica Sinica, 30(3), 355-363 (2009-03-06)
Tumor immunotherapy aims at activating the body's own immune system to fight an existing tumor. Effective antitumor responses require tumor antigens to be presented to lymphocytes. We aimed to test the hypothesis that intratumoral administration of recombinant adenovirus encoding MIP3beta

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