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经验公式(希尔记法):
C11H8O2
化学文摘社编号:
分子量:
172.18
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-372-6
Beilstein/REAXYS Number:
1908453
MDL number:
产品名称
甲萘醌, meets USP testing specifications
Quality Level
InChI key
MJVAVZPDRWSRRC-UHFFFAOYSA-N
InChI
1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
SMILES string
CC1=CC(=O)c2ccccc2C1=O
biological source
synthetic (organic)
agency
USP/NF
meets USP testing specifications
assay
98.5-101.0% dry basis
form
solid
mp
105-107 °C (lit.)
application(s)
pharmaceutical (small molecule)
Gene Information
human ... NQO1(1728)
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Application
甲萘醌已用于:
- 处理 HL-60 细胞作为流式细胞术的凋亡阳性对照
- 作为受精后 24h 后转基因胚胎中的氧化应激诱导剂
- 处理 HaCaT 细胞系,用于定量总谷胱甘肽和氧化谷胱甘肽
Biochem/physiol Actions
甲萘醌是一种氧化应激诱导剂。
General description
甲萘醌(维生素 K3)是维生素 K 的合成形式,具有与维生素 K1、K2 相似的结构。维生素 K1、K2 和 K3 具有生物活性。水溶性形式的甲萘醌用于猪和家禽日粮。
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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