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Merck
CN

M9271

Sigma-Aldrich

α-D-Mannopyranosylphenyl isothiocyanate

>98% (TLC)

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别名:
4-Isothiocyanatophenyl-α-D-mannopyranoside
经验公式(希尔记法):
C13H15NO6S
CAS号:
分子量:
313.33
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

>98% (TLC)

形式

powder

技术

thin layer chromatography (TLC): suitable

杂质

≤5% water (Karl Fischer)

颜色

white to off-white

溶解性

50 mg/mL, clear to very slightly hazy, colorless to light yellow (ACETONE:DIMETHYL SULFOXIDE (7:3))

储存温度

2-8°C

SMILES字符串

OCC1OC(Oc2ccc(cc2)N=C=S)C(O)C(O)C1O

InChI

1S/C13H15NO6S/c15-5-9-10(16)11(17)12(18)13(20-9)19-8-3-1-7(2-4-8)14-6-21/h1-4,9-13,15-18H,5H2

InChI key

RWANFUZQWINQBY-UHFFFAOYSA-N

应用

α-D-Mannopyranosylphenyl isothiocyanate has been used in a study to assess the effect of antigen delivery using a novel mannosylated dendrimer. It has also been used in a study to improve gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates.

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Improvement of gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates
Wada, K., et al.
J. Controlled Release, 104, 397-413 (2005)
Kuo-Ching Sheng et al.
European journal of immunology, 38(2), 424-436 (2008-01-18)
Antigen mannosylation has been shown to be an effective approach to potentiate antigen immunogenicity, due to the enhanced antigen uptake and presentation by APC. To overcome disadvantages associated with conventional methods used to mannosylate antigens, we have developed a novel
M Monsigny et al.
Biology of the cell, 51(2), 187-196 (1984-01-01)
The presence and the sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells were demonstrated by using various neoglycoproteins (glycosylated serum albumin) substituted with fluorescein or methotrexate. Neoglycoproteins were prepared by reaction of glycosidophenylisothiocyanates with

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