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Merck
CN

M9130

4-甲基伞形基β-D-葡糖苷酸 水合物

≥98% (HPLC), BioReagent, for identification of transformed plants

别名:

4-甲基伞形基β-D-吡喃葡糖苷酸, MUG

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关于此项目

经验公式(希尔记法):
C16H16O9 · xH2O
化学文摘社编号:
分子量:
352.29 (anhydrous basis)
NACRES:
NA.52
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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产品名称

4-甲基伞形基β-D-葡糖苷酸 水合物, ≥98% (HPLC), BioReagent, for identification of transformed plants

InChI

1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1

SMILES string

O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12

InChI key

URVSQZMOFUEQAW-YYHOVTOASA-N

grade

Molecular Biology

product line

BioReagent

assay

≥98% (HPLC)

form

powder

solubility

pyridine: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

Quality Level

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Application

适用于对植物中葡萄糖醛酸酶基因的表达进行荧光检测。

General description

MUG是一种常用于检测转化植物的化学品。 在用转化植物中编码的葡萄糖醛酸酶(GUS)处理之前,MUG显示低水平的荧光。 可以通过转化植物的MUG荧光对其进行鉴定。

Preparation Note

产品可以0.35 mg/ml的浓度溶于分子生物级水中。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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L J Moberg
Applied and environmental microbiology, 50(6), 1383-1387 (1985-12-01)
An assay procedure to screen for Escherichia coli in foods by using 4-methylumbelliferyl-beta-D-glucuronide (MUG) incorporated into lauryl tryptose (LST) broth was evaluated. The beta-glucuronidase produced by E. coli cleaves the MUG substrate to yield a fluorescent end product. E. coli-negative
Helena C Besse et al.
Pharmaceutics, 12(6) (2020-06-14)
The poor pharmacokinetics and selectivity of low-molecular-weight anticancer drugs contribute to the relatively low effectiveness of chemotherapy treatments. To improve the pharmacokinetics and selectivity of these treatments, the combination of a doxorubicin-glucuronide prodrug (DOX-propGA3) nanogel formulation and the liberation of
Andrew G Kunihiro et al.
Molecular nutrition & food research, 64(14), e2000072-e2000072 (2020-06-09)
Curcumin prevents bone loss in resorptive bone diseases and inhibits osteoclast formation, a key process driving bone loss. Curcumin circulates as an inactive glucuronide that can be deconjugated in situ by bone's high β-glucuronidase (GUSB) content, forming the active aglycone.
Xiaotian Zhong et al.
The Journal of biological chemistry, 295(10), 3115-3133 (2020-02-02)
The fortuitously discovered antiaging membrane protein αKlotho (Klotho) is highly expressed in the kidney, and deletion of the Klotho gene in mice causes a phenotype strikingly similar to that of chronic kidney disease (CKD). Klotho functions as a co-receptor for
Yuan Ruan et al.
Current biology : CB, 28(17), 2718-2729 (2018-08-28)
The capacity for sustained cell division within the plant meristem is a critical determinant of organ structure and performance. This capacity is diminished in mutants lacking the microtubule-associated protein CLASP and when brassinosteroid signaling is increased. Here, we discovered that

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Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

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