产品名称
IgG1，κ 来源于鼠骨髓瘤, clone MOPC 31C, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
clone
MOPC 31C, monoclonal
assay
≥95% (gel filtration, HPLC)
form
buffered aqueous solution
concentration
≥1 mg/mL
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
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相关类别
Application
来自鼠骨髓瘤的IgG1，κ已用于：
- 染色质免疫沉淀（ChIP）
- 免疫荧光
- 免疫捕获
- 酶免疫测定
- 免疫组织化学
Biochem/physiol Actions
IgG1是最丰富的，其缺乏会导致低丙球蛋白血症。IgG抗体具有巨大的治疗潜力，其Fc区可用于开发治疗性抗体。
特异性通过小鼠单克隆抗体分型试纸条测定。该纯化免疫球蛋白制品与小鼠IgA、IgM、IgG2a、IgG2b和IgG3都不具反应性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
免疫球蛋白（Ig）属于免疫球蛋白超家族。IgG是在人血清中丰富的免疫球蛋白。IgG可分为IgG1、IgG2、IgG3和IgG4四类。
哺乳动物免疫球蛋白含有λ或κ轻链。
Physical form
0.02 MTris 缓冲盐溶液，pH 8.0，含 0.02% 叠氮化钠
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
Margarida Varela Dos Santos et al.
Gynecologic oncology, 176, 76-81 (2023-07-22)
To analyze the expression and prognostic role of L1CAM in tubo-ovarian high-grade serous carcinoma (HGSC). L1CAM protein expression by immunohistochemistry was analyzed in 644 HGSC (413 effusions, 231 surgical specimens). Expression was analyzed for association with clinicopathologic parameters and survival.
Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells
Massey RC, et al.
Cellular Microbiology, 3(12), 839-851 (2001)
Regulation of the transcription factor EB-PGC1alpha axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress
Ma X, et al.
Molecular and Cellular Biology, 35(6), 956-976 (2015)
Margarida Varela Dos Santos et al.
Clinical & experimental metastasis, 41(1), 69-76 (2023-12-23)
The objective of this study was to analyze the expression and prognostic role of the tight junction protein occludin in high-grade serous carcinoma (HGSC). Occludin protein expression by immunohistochemistry was analyzed in 602 HGSC (417 effusions, 185 surgical specimens). Expression
Elisabeth Smogeli et al.
BMC cancer, 16, 596-596 (2016-08-05)
L1 cell adhesion molecule (L1CAM) overexpression has been reported to be strongly associated with poor prognosis in early stage endometrial cancer (EC). We aimed at the validation of L1CAM as a marker of poor prognosis in an independent study population.
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