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Merck
CN
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主要文件

安全信息

M8693

Sigma-Aldrich

Melanotan II 乙酸盐

≥95% (HPLC)

别名:

Ac-[Nle4Asp5D-Phe7Lys10]α-MSH-(4-10)-NH2

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About This Item

经验公式（希尔记法）:
C50H69N15O9 · xC2H4O2
CAS号:
121062-08-6
分子量:
1024.18 (free base basis)
MDL编号:
MFCD06795842
UNSPSC代码:
51111800
NACRES:
NA.32

质量水平

200

方案

≥95% (HPLC)

表单

lyophilized solid

颜色

white

溶解性

H2O: soluble 5 mg/mL

运输

dry ice

储存温度

−20°C

SMILES字符串

[nH]1cncc1C[C@@H]2NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC2=O)Cc5ccccc5)CCCN=C(N)N)Cc3c4c([nH]c3)cccc4)C(=O)N)NC(=O)[C@@H](NC(=O)C)CCCC

InChI

1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1

InChI key

JDKLPDJLXHXHNV-MFVUMRCOSA-N

基因信息

human ... MC3R(4159) , MC4R(4160)
mouse ... MC3R(17201) , MC4R(17202)
rat ... MC3R(29310) , MC4R(25635)

Amino Acid Sequence

Ac-Nle-Asp-His-Phe-Arg-Trp-Lys-NH2

一般描述

Melanotan II诱导黑色素生成，从而增加皮肤色素沉着。是α-黑素细胞刺激素的类似物。

应用

Melanotan II乙酸盐已被用于研究其对大鼠进食和能量消耗的抑制作用。

生化/生理作用

Melanotan II 是一种 MC3-R/MC4-R 黑皮质素激动剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000232818
0000133014
0000133014
0000232818
0000096430

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