一般描述
黑色素是存在于脊椎动物表面结构中的重要色素，可导致皮肤变色。它具有三种形式，如：真黑素(eumelanin)，褐黑素(pheomelanin)，神经黑素(neuromelanin)。黑色素具有阳离子螯合和氧化还原特性。它是强效的光吸收剂。黑色素起化学保护和光保护性颜料的作用。该基因的突变与眼白化病、白癜风、花斑病和瓦登伯格综合征有关。
应用
黑色素已用于：
- 分光光度法测定
- 研究其对逆转录聚合酶链式反应(RT-PCR)的抑制作用以及BSA（牛血清白蛋白）在克服抑制作用方面的作用
- 用作近红外组织光谱中皮肤层的吸收剂
- 拉曼光谱分析
制备说明
通过使用过氧化氢对酪氨酸进行氧化制备。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Fengmei Zou et al.
Biomedical optics express, 1(3), 748-761 (2011-01-25)
An accurate SO(2) prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least
Justyna M Drewnowska et al.
PloS one, 10(4), e0125428-e0125428 (2015-04-25)
Although melanin is known for protecting living organisms from harmful physical and chemical factors, its synthesis is rarely observed among endospore-forming Bacillus cereus sensu lato. Here, for the first time, we reported that psychrotolerant Bacillus weihenstephanensis from Northeastern Poland can
Bovine serum albumin reverses inhibition of RT-PCR by melanin
Giambernardi TA, et al.
Biotechniques, 25(4), 564-566 (1998)
Melanin
Riley PA
The International Journal of Biochemistry & Cell Biology, 29(11), 1235-1239 (1997)
Constant rate of steady-state self-antigen trafficking from skin to regional lymph nodes
Yoshino M, et al.
International Immunology, 18(11), 1541-1548 (2006)
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