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Merck
CN

M8574

Sigma-Aldrich

D-(+)-甘露糖

synthetic, ≥99% (GC)

别名:

D-吡喃甘露糖

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About This Item

经验公式(希尔记法):
C6H12O6
CAS号:
分子量:
180.16
Beilstein:
1564373
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

生物来源

synthetic

质量水平

方案

≥99% (GC)

表单

powder

旋光性

[α]25/D 13.5 to 14.9 °, c = 4% (w/v) in water

技术

gas chromatography (GC): suitable

颜色

white to off-white

mp

133-140 °C (lit.)

溶解性

water: soluble 10 g/L at 20 °C

储存温度

room temp

SMILES字符串

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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应用

D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.

生化/生理作用

Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Simone Torretta et al.
Nature communications, 11(1), 6343-6343 (2020-12-15)
D-mannose is a monosaccharide approximately a hundred times less abundant than glucose in human blood. Previous studies demonstrated that supraphysiological levels of D-mannose inhibit tumour growth and stimulate regulatory T cell differentiation. It is not known whether D-mannose metabolism affects
Brett Shannon et al.
Journal of immunology (Baltimore, Md. : 1950), 192(11), 5074-5082 (2014-04-25)
HSV-2 infection is common and generally asymptomatic, but it is associated with increased HIV susceptibility and disease progression. This may relate to herpes-mediated changes in genital and systemic immunology. Cervical cytobrushes and blood were collected from HIV-uninfected African/Caribbean women in
Charles D Murin et al.
Journal of virology, 88(17), 10177-10188 (2014-06-27)
The neutralizing anti-HIV-1 antibody 2G12 is of particular interest due to the sterilizing protection it provides from viral challenge in animal models. 2G12 is a unique, domain-exchanged antibody that binds exclusively to conserved N-linked glycans that form the high-mannose patch
Ana Sofia Carvalho et al.
Molecular & cellular proteomics : MCP, 13(12), 3294-3307 (2014-08-17)
We investigated the molecular effects of glucosamine supplements, a popular and safe alternative to nonsteroidal anti-inflammatory drugs, for decreasing pain, inflammation, and maintaining healthy joints. Numerous studies have reported an array of molecular effects after glucosamine treatment. We questioned whether
Varnica Khetrapal et al.
Nucleic acids research, 43(13), e83-e83 (2015-03-25)
Creation of defined genetic mutations is a powerful method for dissecting mechanisms of bacterial disease; however, many genetic tools are only developed for laboratory strains. We have designed a modular and general negative selection strategy based on inducible toxins that

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