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主要文件

安全信息

M7894

Sigma-Aldrich

IgG1,κ 来源于鼠骨髓瘤

clone MOPC 21, ascites fluid, lyophilized powder

别名:

小鼠 IgG1-κ

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5 ML
¥1,541.27
10 X 1 ML
¥2,460.67
25 ML
¥4,616.17

¥1,541.27


国内现货,预计发货时间2025年4月27日详情


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选择尺寸

变更视图
5 ML
¥1,541.27
10 X 1 ML
¥2,460.67
25 ML
¥4,616.17

About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

¥1,541.27


国内现货,预计发货时间2025年4月27日详情


获取大包装报价

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

ascites fluid

克隆

MOPC 21, monoclonal

表单

lyophilized powder

应用

research pathology

储存温度

2-8°C

靶向翻译后修饰

unmodified

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69478M7891394866
assay

≥98.5% (GC)

assay

≥97.0%

assay

-

assay

≥98%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

-

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

bp

130-132 °C (lit.)

bp

-

bp

130-132 °C (lit.)

bp

130-132 °C (lit.)

form

liquid

form

liquid

form

liquid

form

liquid

density

1.075 g/mL at 25 °C (lit.)

density

-

density

1.07 g/mL at 25 °C (lit.), 1.075 g/mL at 25 °C (lit.)

density

1.075 g/mL at 25 °C (lit.)

一般描述

The MOPC-21 tumor line that produces mouse IgG1, κ is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulins G are made up of two identical light chains and two identical heavy chains, that are covalently connected by interchain disulphide bonds.[1] Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b, IgG2c and IgG3.[2]

应用

IgG1, Kappa from murine myeloma has been used:
  • in stimulation assay and enzyme-linked immunosorbent assay (ELISA)[3]
  • as isotype controls in islet hormone production[4]
  • in flow cytometric analysis[5], in cell migration assay[6]
  • as control antibody in evaluation of methylation[7]

生化/生理作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.[8]
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions.[9] IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.[2]

重悬

Reconstitute with 1 mL deionized water.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
  • 技术规格说明书

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Eva Obermueller et al.
    Cancer research, 64(21), 7801-7812 (2004-11-03)
    Tumor growth and progression are critically controlled by alterations in the microenvironment often caused by an aberrant expression of growth factors and receptors. We demonstrated previously that tumor progression in patients and in the experimental HaCaT tumor model for skin
    J Zhu et al.
    American journal of respiratory and critical care medicine, 164(12), 2220-2228 (2001-12-26)
    We wished to determine if the inflammatory cells surrounding the airway mucus-secreting glands in chronic bronchitis (CB) were associated with interleukin (IL)-4 and IL-5 mRNA expression and whether the CD8 T cell population expressed these cytokines. Digoxigenin-labeled IL-4 and IL-5
    M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis
    Schlapbach LJ, et al.
    Pediatric Research, 71(4-1), 368-368 (2012)
    IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines
    Lederle W, et al.
    International Journal of Cancer. Journal International Du Cancer, 128(12), 2803-2814 (2011)
    The Laboratory Rat (2015)

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