M7659
肌球蛋白重链 来源于兔肌肉
buffered aqueous glycerol solution
别名:
ATPase inactive whole chain myosin
产品名称
肌球蛋白重链 来源于兔肌肉, buffered aqueous glycerol solution
biological source
rabbit muscle
form
buffered aqueous glycerol solution
technique(s)
electrophoresis: suitable
UniProt accession no.
foreign activity
ATPase Activity ≤0.01 units/mg protein
storage temp.
−20°C
Quality Level
Gene Information
rabbit ... PBV1SPCR2(100009284)
Application
Myosin Heavy Chain from rabbit muscle has been used:
- in SDS analysis of myosin heavy chain (MHC) composition and content
- for microinjection into the outflow of heart (blood serum) and the cephalic cavities (embryonic cerebrospinal fluid) of chick embryo
- as a muscle protein, to study the role of ascorbate as a facilitator of glycogen storage in muscles
Biochem/physiol Actions
Molecular motor involved in the contraction of muscles.
General description
Myosin heavy chain (MHC) is a motor protein of muscle thick filaments. MHC regulates ultrastructural diversity of myofibrils.
Physical form
Solution in 50% glycerol containing 0.6 M KCl and 0.005 M potassium phosphate, pH 6.5
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Myosin heavy chain isoforms regulate muscle function but not myofibril assembly.
Wells L, et al.
The Embo Journal, 15(17), 4454-4459 (1996)
Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse
Kemp JG, et al.
International journal of obesity (2005), 33(8), 831-831 (2009)
L Wells et al.
The EMBO journal, 15(17), 4454-4459 (1996-09-02)
Myosin heavy chain (MHC) is the motor protein of muscle thick filaments. Most organisms produce many muscle MHC isoforms with temporally and spatially regulated expression patterns. This suggests that isoforms of MHC have different characteristics necessary for defining specific muscle
I Morano
Journal of molecular medicine (Berlin, Germany), 77(7), 544-555 (1999-09-24)
Cardiac contraction is triggered by the cyclic interaction of the "molecular motor" protein myosin with the actin filament, consuming ATP as the energy source to produce tension or shortening. The myosin heavy chain (MHC) contains the actin- and ATP-binding sites
A blood-CSF barrier function controls embryonic CSF protein composition and homeostasis during early CNS development
Parvas M, et al.
Developmental Biology, 321(1), 51-63 (2008)
商品
Myosins are a family of ATP-dependent motor proteins. Myosin II is the major contractile protein involved in eukaryotic muscle contraction by “walking” along actin microfilaments of the sarcomere
肌球蛋白是ATP依赖性运动蛋白家族。肌球蛋白II是真核肌肉收缩的主要收缩蛋白，通过沿着肌动蛋白微丝“行走”参与肌肉收缩。
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