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生物来源
rabbit muscle
质量水平
表单
buffered aqueous glycerol solution
技术
electrophoresis: suitable
UniProt登记号
异质活性
ATPase Activity ≤0.01 units/mg protein
储存温度
−20°C
基因信息
rabbit ... PBV1SPCR2(100009284)
一般描述
Myosin heavy chain (MHC) is a motor protein of muscle thick filaments. MHC regulates ultrastructural diversity of myofibrils.
应用
Myosin Heavy Chain from rabbit muscle has been used:
- in SDS analysis of myosin heavy chain (MHC) composition and content
- for microinjection into the outflow of heart (blood serum) and the cephalic cavities (embryonic cerebrospinal fluid) of chick embryo
- as a muscle protein, to study the role of ascorbate as a facilitator of glycogen storage in muscles
生化/生理作用
Molecular motor involved in the contraction of muscles.
外形
Solution in 50% glycerol containing 0.6 M KCl and 0.005 M potassium phosphate, pH 6.5
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse
Kemp JG, et al.
International journal of obesity (2005), 33(8), 831-831 (2009)
Myosin heavy chain isoforms regulate muscle function but not myofibril assembly.
Wells L, et al.
The Embo Journal, 15(17), 4454-4459 (1996)
L Wells et al.
The EMBO journal, 15(17), 4454-4459 (1996-09-02)
Myosin heavy chain (MHC) is the motor protein of muscle thick filaments. Most organisms produce many muscle MHC isoforms with temporally and spatially regulated expression patterns. This suggests that isoforms of MHC have different characteristics necessary for defining specific muscle
I Morano
Journal of molecular medicine (Berlin, Germany), 77(7), 544-555 (1999-09-24)
Cardiac contraction is triggered by the cyclic interaction of the "molecular motor" protein myosin with the actin filament, consuming ATP as the energy source to produce tension or shortening. The myosin heavy chain (MHC) contains the actin- and ATP-binding sites
A blood-CSF barrier function controls embryonic CSF protein composition and homeostasis during early CNS development
Parvas M, et al.
Developmental Biology, 321(1), 51-63 (2008)
商品
Myosins are a family of ATP-dependent motor proteins. Myosin II is the major contractile protein involved in eukaryotic muscle contraction by “walking” along actin microfilaments of the sarcomere
肌球蛋白是ATP依赖性运动蛋白家族。肌球蛋白II是真核肌肉收缩的主要收缩蛋白，通过沿着肌动蛋白微丝“行走”参与肌肉收缩。
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