推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
whole antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
包含
15 mM sodium azide
种属反应性
animal, human
技术
indirect immunofluorescence: 1:10 using cultured fibroblasts
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MYH10(4628) , MYH9(4627) , MYL9(10398)
一般描述
Myosin is a 500 kD protein that interacts with actin in muscle and in non-muscle cells. It is characterized with two identical heavy chains (200 kD each) and four light chains (15-20 kD each). Myosin molecules consist of two major regions; the tail (rod) and head. These molecules aggregate into filaments through the tail region and interact with actin and ATP through the head region.
特异性
Shows a pattern of staining along stress fibers of cultured human and animal fibroblasts.
免疫原
whole myosin (heavy and light chains) from bovine uterus.
应用
Anti-Myosin (Skeletal and Smooth) antibody produced in rabbit has been used in indirect immunofluorescence labeling.
生化/生理作用
Myosin plays a vital role in neurosensory and cortical function, membrane vesicle trafficking and determinant partitioning. Myosins with actin-stimulated ATPase activity is essential for various cellular movements. Myosins I and V mediates vesicle translocation. Myosin II with a long rod like tail domain, assembles into a bipolar thick filament and facilitate muscle contraction.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
F Baluska et al.
Developmental biology, 227(2), 618-632 (2000-11-10)
Plant root hair formation is initiated when specialized elongating root epidermis cells (trichoblasts) assemble distinct domains at the plasma membrane/cell wall cell periphery complexes facing the root surface. These localities show accumulation of expansin and progressively transform into tip-growing root
Myosin: The Actin Motor Protein
Molecular Cell Biology, 10(1), 80-86 (2000)
Root hair formation: F-actin-dependent tip growth is initiated by local assembly of profilin-supported F-actin meshworks accumulated within expansin-enriched bulges
Baluska F, et al.
Developmental Biology, 227(2), 618-632 (2000)
The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions?a novel architectonic cell-cell junction system
Domke LM and Franke WW
Cell and Tissue Research, 375(2), 451-482 (2019)
Myosins: matching functions with motors.
Baker JP and Titus MA.
Current Opinion in Cell Biology, 10(1), 80-86 (1998)
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