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质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
white to off-white
溶解性
acetone: 1 mg/mL, clear, colorless
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
2-8°C
SMILES字符串
CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
InChI
1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1
InChI key
MDZKJHQSJHYOHJ-LLICELPBSA-N
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一般描述
山楂酸是一种五环三萜类化合物，最早从锐刺山楂中分离得到。 它主要来源于油橄榄，并存在于橄榄果渣的非甘油酯部分。
应用
山楂酸已被用于研究其对人肾细胞癌 (RCC) 细胞系和内皮细胞的抗增殖和抗血管生成作用。它还用作参考标准品，通过微波辅助萃取 (MAE) 法从橄榄果渣中提取三萜酸。
生化/生理作用
山楂酸是一种强效抗氧化剂和抗炎剂。除了是一种良好的抗癌剂外，它还具有抗糖尿病和抗寄生虫的特性。山楂酸具有神经保护和心脏保护作用。据报道它是一种针对恶性疟原虫的多靶点抗疟药。
在橄榄中发现的主要三萜类化合物。抗增殖。有前景的化学预防剂。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Parth Thakor et al.
Journal of kidney cancer and VHL, 4(1), 16-24 (2017-04-14)
Despite the introduction of many novel therapeutics in clinical practice, metastatic renal cell carcinoma (RCC) remains a treatment-resistant cancer. As red and processed meat are considered risk factors for RCC, and a vegetable-rich diet is thought to reduce this risk
Ana Márquez Martín et al.
Free radical research, 40(3), 295-302 (2006-02-18)
The pentacyclic triterpene maslinic acid (MA) is a natural compound present in the non glyceride fraction of pomace olive oil, also called orujo olive oil. This compound has previously demonstrated antioxidant properties against lipid peroxidation in vitro, but its effects
Optimisation of microwave-assisted extraction of triterpenoic acids from olive mill waste using response surface methodology
Ozkan G, et al.,
Quality Assurance and Safety of Crops & Foods, 9(2), 179-185 (2017)
Yan Sun et al.
Talanta, 205, 120011-120011 (2019-08-28)
A fast and simple analytical method was developed to fully understand the chemical diversity of pentacyclic triterpenes: lupane, oleanane and ursane type, using multiple neutral loss markers scanning combined with substructure recognition (MNLSR). This procedure was performed on ultra-high performance
Susana Sánchez-Tena et al.
PloS one, 8(3), e59392-e59392 (2013-03-26)
Chemoprevention is a pragmatic approach to reduce the risk of colorectal cancer, one of the leading causes of cancer-related death in western countries. In this regard, maslinic acid (MA), a pentacyclic triterpene extracted from wax-like coatings of olives, is known
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