InChI key
MDZKJHQSJHYOHJ-LLICELPBSA-N
SMILES string
CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
InChI
1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
acetone: 1 mg/mL, clear, colorless
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
山楂酸是一种五环三萜类化合物,最早从锐刺山楂中分离得到。 它主要来源于油橄榄,并存在于橄榄果渣的非甘油酯部分。
Application
山楂酸已被用于研究其对人肾细胞癌 (RCC) 细胞系和内皮细胞的抗增殖和抗血管生成作用。它还用作参考标准品,通过微波辅助萃取 (MAE) 法从橄榄果渣中提取三萜酸。
Biochem/physiol Actions
在橄榄中发现的主要三萜类化合物。抗增殖。有前景的化学预防剂。
山楂酸是一种强效抗氧化剂和抗炎剂。除了是一种良好的抗癌剂外,它还具有抗糖尿病和抗寄生虫的特性。山楂酸具有神经保护和心脏保护作用。据报道它是一种针对恶性疟原虫的多靶点抗疟药。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Parth Thakor et al.
Journal of kidney cancer and VHL, 4(1), 16-24 (2017-04-14)
Despite the introduction of many novel therapeutics in clinical practice, metastatic renal cell carcinoma (RCC) remains a treatment-resistant cancer. As red and processed meat are considered risk factors for RCC, and a vegetable-rich diet is thought to reduce this risk
Ana Márquez Martín et al.
Free radical research, 40(3), 295-302 (2006-02-18)
The pentacyclic triterpene maslinic acid (MA) is a natural compound present in the non glyceride fraction of pomace olive oil, also called orujo olive oil. This compound has previously demonstrated antioxidant properties against lipid peroxidation in vitro, but its effects
Yan Sun et al.
Talanta, 205, 120011-120011 (2019-08-28)
A fast and simple analytical method was developed to fully understand the chemical diversity of pentacyclic triterpenes: lupane, oleanane and ursane type, using multiple neutral loss markers scanning combined with substructure recognition (MNLSR). This procedure was performed on ultra-high performance
W H Yap et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(2), 183-191 (2011-09-07)
Maslinic acid, a natural pentacyclic triterpene has been shown to inhibit growth and induce apoptosis in some tumour cell lines. We studied the molecular response of Raji cells towards maslinic acid treatment. A proteomics approach was employed to identify the
Longfei Huang et al.
European journal of pharmacology, 672(1-3), 169-174 (2011-10-06)
Maslinic acid (2-α, 3-β-dihydroxyolean-12-en-28-oic acid) is a natural triterpenoid compound from Olea europaea. This compound prevents oxidative stress and pro-inflammatory cytokine generation in vitro. This study was planned to investigate the anti-inflammatory effects of maslinic acid in central nervous system
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持