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Merck
CN

M6546

(±)-2-(对甲氧基苯氧基)丙酸

solid, ≥98%

别名:

PMP

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关于此项目

经验公式(希尔记法):
C10H12O4
化学文摘社编号:
分子量:
196.20
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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产品名称

(±)-2-(对甲氧基苯氧基)丙酸, ≥98%

biological source

synthetic (organic)

Quality Level

assay

≥98%

form

solid

SMILES string

COc1ccc(OC(C)C(O)=O)cc1

InChI

1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

InChI key

MIEKOFWWHVOKQX-UHFFFAOYSA-N

Application

(±)-2-(对甲氧基苯氧基)丙酸可作为甜味受体拮抗剂,研究其对大鼠糖诱导胰高血糖素样肽1(GLP-1)分泌的影响。它也可用于研究分泌素肿瘤细胞系(STC-1)在(±)-2-(对甲氧基苯氧基)丙酸或乳清存在及不存在环境下对甜味剂的反应。

Biochem/physiol Actions

作为一种味觉调节剂,钠盐可以抑制人对甜味的感知,但对大鼠却没有影响。


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiulian Li et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(3), 1220-1234 (2017-10-06)
Bleomycin is a clinically used anti-cancer drug that produces DNA breaks once inside of cells. However, bleomycin is a positively charged molecule and cannot get inside of cells by free diffusion. We previously reported that the cell surface negatively charged
Paolo Tommasino et al.
Frontiers in neurorobotics, 11, 65-65 (2017-12-19)
A major challenge in robotics and computational neuroscience is relative to the posture/movement problem in presence of kinematic redundancy. We recently addressed this issue using a principled approach which, in conjunction with nonlinear inverse optimization, allowed capturing postural strategies such
Li-Chun Chen et al.
Food chemistry, 212, 768-777 (2016-07-05)
The biological functions of cell membranes strongly influence the binding and transport of molecular species. We developed STC-1 cell line stably expressing the sweet taste receptor (T1R2/T1R3), and explored the possible correlation between sweeteners and membrane dipole potential of STC-1



全球贸易项目编号

货号GTIN
M6546-100MG04061832948225
M6546-500MG04061832948232