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M6403

(±)-3,4-亚甲二氧基甲基苯异丙胺盐酸盐

Name: (±)-3,4-亚甲二氧基甲基苯异丙胺 盐酸盐
Brand: SIGMA

别名:

(±)-MDMA 盐酸盐, DL-3,4-亚甲二氧基甲基苯异丙胺, DL-MDMA 盐酸盐, XTC 盐酸盐, 摇头丸

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About This Item

经验公式（希尔记法）:

C₁₁H₁₅NO₂ · HCl

CAS号:

64057-70-1

分子量:

229.70

MDL编号:

MFCD00079444

UNSPSC代码:

12352116

PubChem化学物质编号:

24897006

NACRES:

NA.77

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M-013

3,4-亚甲基二氧基甲基苯丙胺标准液（MDMA）溶液

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M6267

(±)-3,4-亚甲二氧基苯异丙胺盐酸盐

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M8750

(+)-甲基苯丙胺盐酸盐

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M-011

（±）-MDMA-D₅ 溶液

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L7007

麦角酸二乙基酰胺

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M-009

(±)-甲基苯丙胺标准液溶液

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K-002

盐酸氯胺酮标准液盐酸盐溶液

Supelco

M-012

3,4-亚甲基双氧苯丙胺标准液溶液

Sigma-Aldrich

M1796

(±)-3,4-甲二氧基-N-乙基苯丙胺盐酸盐

质量水平

200

药品控制

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

技术

HPLC: suitable
gas chromatography (GC): suitable

溶解性

H₂O: soluble

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

SMILES字符串

Cl[H].CNC(C)Cc1ccc2OCOc2c1

InChI

1S/C11H15NO2.ClH/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10;/h3-4,6,8,12H,5,7H2,1-2H3;1H

InChI key

LUWHVONVCYWRMZ-UHFFFAOYSA-N

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生化/生理作用

迷幻剂；从轴突终末释放羟色胺和多巴胺；选择性血清素能神经毒素。

象形图

GHS06

警示用语：

Danger

危险声明

H301,H336

预防措施声明

P301 + P310 + P330

危险分类

Acute Tox. 3 Oral - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum.

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Ecstasy is a popular recreational psychostimulant with side effects on the central nervous system. This study examined the corpus striatum tissue of adult rats that received ecstasy during the embryonic period for histological and molecular studies. Rats were divided into

Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration.

M I Colado et al.

British journal of pharmacology, 126(4), 911-924 (1999-04-08)

1. We investigated whether dopamine plays a role in the neurodegeneration of 5-hydroxytryptamine (5-HT) nerve endings occurring in Dark Agouti rat brain after 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration. 2. Haloperidol (2 mg kg(-1) i.p.) injected 5 min prior and 55

Investigation of the prejunctional alpha2-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens.

A Lavelle et al.

British journal of pharmacology, 128(5), 975-980 (1999-11-11)

1. We have investigated the effects of methylenedioxymethamphetamine (MDMA, 'ecstasy') on peripheral noradrenergic neurotransmission in the rat. 2. In rat atrial slices pre-incubated with [3H]-noradrenaline and in the presence of desipramine (1 micronM) to prevent effects of MDMA on basal

(+/-)3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: studies in animals.

G A Ricaurte et al.

Neuropsychobiology, 42(1), 5-10 (2000-06-27)

The popular recreational drug, (+/-)3, 4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be demonstrated using a variety of neurochemical, neuroanatomical and, more recently, functional measures of 5-HT neurons. Although

Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulata, and the dorsal raphé nucleus slices.

M M Iravani et al.

Synapse (New York, N.Y.), 36(4), 275-285 (2000-05-20)

We examined the effects of pressure ejected 3, 4-methylenedioxymethamphetamine (MDMA) from a micropipette on direct chemically stimulated release, and on electrically stimulated serotonin (5-HT) or dopamine (DA) release in the caudate putamen (CPu), nucleus accumbens (NAc), substantia nigra pars reticulata

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