M6013
甲羟孕酮
别名:
17α-羟基-6α-甲基-4-孕烯-3,20-二酮, 17α-羟基-6α-甲基孕酮, 6α-甲基-5-孕甾烯-17α-醇-3,20-二酮, 6-二氢甲地孕酮
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关于此项目
经验公式（希尔记法）:
C22H32O3
化学文摘社编号:
分子量:
344.49
UNSPSC Code:
51111800
NACRES:
NA.77
PubChem Substance ID:
EC Number:
208-298-6
Beilstein/REAXYS Number:
2510965
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥98% (HPLC)
InChI key
FRQMUZJSZHZSGN-HBNHAYAOSA-N
InChI
1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
SMILES string
[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O
biological source
synthetic (organic)
assay
≥98% (HPLC)
form
powder
solubility
chloroform: 50 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
Quality Level
Gene Information
rat ... Ar(24208)
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Disclaimer
Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
涉药品监管产品
此项目有
Adarsh J Sai et al.
Menopause (New York, N.Y.), 18(10), 1101-1112 (2011-06-30)
The aim of this study was to examine the effect of conjugated equine estrogens alone (ET), conjugated equine estrogens + medroxyprogesterone (EPT), calcitriol alone, calcitriol + EPT/ET, or placebo on serum lipid profile and analyze the interaction with estrogen receptor-α
M F Fung et al.
Obstetrics and gynecology, 78(6), 1033-1038 (1991-12-01)
We conducted a retrospective review of 44 patients with metastatic or recurrent endometrial carcinoma treated with cisplatin, doxorubicin, cyclophosphamide, and medroxyprogesterone acetate. Thirty-six women had metastatic disease; eight had recurrent disease. In the metastatic group, 12 women had positive peritoneal
Clinical significance of differences in bioavailability of medroxyprogesterone acetate preparations.
A D Stockdale et al.
Clinical pharmacokinetics, 16(3), 129-133 (1989-03-01)
A Günzel-Apel et al.
Reproduction in domestic animals = Zuchthygiene, 47 Suppl 6, 55-60 (2013-01-04)
Progesterone profiles of individual bitches may vary considerably both between and within individuals during pregnancy and non-pregnancy. Suspected luteal deficiency is commonly purported but is difficult to evaluate in clinical cases when progesterone is supplemented because this masks the underlying
The role of medroxyprogesterone acetate (MPA) in the treatment of renal adenocarcinoma.
M Kjaer
Cancer treatment reviews, 15(3), 195-209 (1988-09-01)
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